Melanin-concentrating hormone (MCH) receptor (nonspecified subtype)
Review Report on Melanin-concentrating hormone (MCH) receptor (nonspecified subtype) Target / Biomarker Content of Review Report on Melanin-concentrating hormone (MCH) receptor (nonspecified subtype) Target / Biomarker
Melanin-concentrating hormone (MCH) receptor (nonspecified subtype)

Related Diseases

1) Metabolic Syndrome
Abdominal Obesity-Metabolic Syndrome 1, also known as metabolic syndrome x, is related to mandibular hypoplasia, deafness, progeroid features, and lipodystrophy syndrome and nutritional deficiency disease, and has symptoms including angina pectoris, chest pain and edema. An important gene associated with Abdominal Obesity-Metabolic Syndrome 1 is MIR122 (MicroRNA 122), and among its related pathways/superpathways are Metabolism and IL-9 Signaling Pathways. The drugs Cilostazol and Captopril have been mentioned in the context of this disorder. Affiliated tissues include heart, liver and adipocyte, and related phenotypes are hypertension and abdominal obesity

2) Diabetes Type 2
Type 2 Diabetes Mellitus, also known as insulin resistance, is related to diabetes mellitus and maturity-onset diabetes of the young, type 8, with exocrine dysfunction, and has symptoms including angina pectoris, tremor and equilibration disorder. An important gene associated with Type 2 Diabetes Mellitus is IRS1 (Insulin Receptor Substrate 1), and among its related pathways/superpathways are Nervous system development and Angiopoietin-like protein 8 regulatory pathway. The drugs Glipizide and Glycopyrronium have been mentioned in the context of this disorder. Affiliated tissues include Pancreas and Adipose, and related phenotypes are type ii diabetes mellitus and insulin resistance

3) Depression
Major Depressive Disorder, also known as seasonal affective disorder, is related to anxiety and endogenous depression, and has symptoms including affective symptoms, behavioral symptoms and schizophrenic language. An important gene associated with Major Depressive Disorder is HTR2A (5-Hydroxytryptamine Receptor 2A), and among its related pathways/superpathways are Signal Transduction and Neuroscience. The drugs Fluvoxamine and Valsartan have been mentioned in the context of this disorder. Affiliated tissues include brain, prefrontal cortex and cortex, and related phenotypes are depression and behavior/neurological

4) Anxiety Disorders
Anxiety, also known as anxiety disorders, is related to generalized anxiety disorder and separation anxiety disorder, and has symptoms including nervousness, agitation and feeling tense. An important gene associated with Anxiety is SLC6A4 (Solute Carrier Family 6 Member 4), and among its related pathways/superpathways are Signal Transduction and Class A/1 (Rhodopsin-like receptors). The drugs Amlodipine and Lorazepam have been mentioned in the context of this disorder. Affiliated tissues include brain, breast and thyroid, and related phenotypes are nervous system and normal

5) Epilepsy
Epilepsy, also known as epilepsy syndrome, is related to epilepsy, myoclonic juvenile and childhood absence epilepsy, and has symptoms including back pain, headache and pain. An important gene associated with Epilepsy is SCN1A (Sodium Voltage-Gated Channel Alpha Subunit 1), and among its related pathways/superpathways are Neuropathic Pain-Signaling in Dorsal Horn Neurons and Neuroscience. The drugs Ethosuximide and Vigabatrin have been mentioned in the context of this disorder. Affiliated tissues include brain, temporal lobe and thalamus, and related phenotypes are nervous system and growth/size/body region

6) Sleep Apnea
Sleep Apnea, also known as sleep apnea syndromes, is related to central sleep apnea and obesity-hypoventilation syndrome, and has symptoms including apnea, back pain and cheyne-stokes respiration. An important gene associated with Sleep Apnea is AHDC1 (AT-Hook DNA Binding Motif Containing 1), and among its related pathways/superpathways are Signal Transduction and p70S6K Signaling. The drugs Montelukast and Opium have been mentioned in the context of this disorder. Affiliated tissues include heart, lung and tongue, and related phenotypes are homeostasis/metabolism and nervous system

7) Anorexia Nervosa
Anorexia Nervosa, also known as anorexia nervosa, susceptibility to, is related to eating disorder and body dysmorphic disorder, and has symptoms including decrease in appetite An important gene associated with Anorexia Nervosa is HTR2A (5-Hydroxytryptamine Receptor 2A), and among its related pathways/superpathways are GPCR downstream signalling and Signal Transduction. The drugs Aripiprazole and Fluoxetine have been mentioned in the context of this disorder. Affiliated tissues include bone, brain and prefrontal cortex, and related phenotypes are Reduced mammosphere formation and nervous system

8) Bulimia Nervosa
Bulimia Nervosa, also known as bulimia, is related to abdominal obesity-metabolic syndrome 1 and polysubstance abuse, and has symptoms including salt craving, symptoms and decrease in appetite. An important gene associated with Bulimia Nervosa is BULN (Bulimia Nervosa, Susceptibility To), and among its related pathways/superpathways are Signal Transduction and GPCR downstream signalling. The drugs Memantine and Sibutramine have been mentioned in the context of this disorder. Affiliated tissues include thyroid, prefrontal cortex and skin, and related phenotypes are bulimia and nervous system

9) Diabetes
Diabetes Mellitus, also known as diabetes, is related to type 2 diabetes mellitus and gestational diabetes, and has symptoms including angina pectoris, tremor and equilibration disorder. An important gene associated with Diabetes Mellitus is KCNJ11 (Potassium Inwardly Rectifying Channel Subfamily J Member 11), and among its related pathways/superpathways are Regulation of beta-cell development and Cell differentiation - expanded index. The drugs Miconazole and Clotrimazole have been mentioned in the context of this disorder. Affiliated tissues include pancreas, bone marrow and kidney.

10) Hepatic Steatosis
Fatty Liver Disease, Nonalcoholic 1, also known as nafld1, is related to non-alcoholic fatty liver disease and fatty liver disease. An important gene associated with Fatty Liver Disease, Nonalcoholic 1 is ATG7 (Autophagy Related 7). The drugs Metformin and Entecavir have been mentioned in the context of this disorder. Affiliated tissues include liver, skeletal muscle and kidney, and related phenotype is hepatic steatosis.

11) Obesity
Body Mass Index Quantitative Trait Locus 11, also known as obesity, is related to leptin deficiency or dysfunction and type 2 diabetes mellitus, and has symptoms including high weight, symptoms and obesity, metabolically benign. An important gene associated with Body Mass Index Quantitative Trait Locus 11 is UCP3 (Uncoupling Protein 3), and among its related pathways/superpathways are Beta-2 adrenergic-dependent CFTR expression and Glucose / Energy Metabolism. The drugs Hydrocortisone and Hydrocortisone succinate have been mentioned in the context of this disorder. Affiliated tissues include skeletal muscle, liver and heart, and related phenotypes are obesity and decreased resting energy expenditure

12) Nutrition Disorders
Nutritional Deficiency Disease, also known as malnutrition, is related to folic acid deficiency anemia and iron deficiency anemia, and has symptoms including abdominal pain, cachexia and constipation. An important gene associated with Nutritional Deficiency Disease is TTR (Transthyretin), and among its related pathways/superpathways are Metabolism of proteins and Glucose / Energy Metabolism. The drugs Heparin, bovine and Tramadol have been mentioned in the context of this disorder. Affiliated tissues include liver, skeletal muscle and breast, and related phenotypes are no effect and no effect

13) Dyslipidemia
Lipid Metabolism Disorder, also known as dyslipidemia, is related to hyperlipoproteinemia, type iii and hypobetalipoproteinemia, familial, 1. An important gene associated with Lipid Metabolism Disorder is LIPC (Lipase C, Hepatic Type), and among its related pathways/superpathways are Metabolism and Transport of inorganic cations/anions and amino acids/oligopeptides. The drugs Tocopherol and Aripiprazole have been mentioned in the context of this disorder. Affiliated tissues include liver, heart and bone marrow, and related phenotypes are no effect and no effect

14) Eating Disorder
Eating Disorder, also known as eating disorders, is related to bulimia nervosa and anorexia nervosa, and has symptoms including decrease in appetite, adipsia and symptoms concerning nutrition, metabolism, and development. An important gene associated with Eating Disorder is GHRL (Ghrelin And Obestatin Prepropeptide), and among its related pathways/superpathways are GPCR downstream signalling and Signal Transduction. The drugs Zinc sulfate and Zinc cation have been mentioned in the context of this disorder. Affiliated tissues include brain, heart and kidney, and related phenotypes are Weakly decreased NFAT1-GFP nuclear translocation and homeostasis/metabolism

The "Melanin-concentrating hormone (MCH) receptor (nonspecified subtype) Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about Melanin-concentrating hormone (MCH) receptor (nonspecified subtype) comprehensively including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

11beta-Hydroxysteroid Dehydrogenase | 14-3-3 Protein | 15-Lipoxygenase | 17-beta-Hydroxysteroid dehydrogenase | 28S ribosomal subunit, mitochondrial | 3-Ketoacyl-CoA Thiolase (3-KAT) | 39S ribosomal subunit, mitochondrial | 4EHP-GYF2 complex | 5-Hydroxytryptamine Receptor | 5-Hydroxytryptamine Receptor 1 (5-HT1) | 5-Hydroxytryptamine Receptor 2 (5-HT2) | 60S Ribosome | 9-1-1 cell-cycle checkpoint response complex | A-Kinase Anchor Proteins | A1BG | A1BG-AS1 | A1CF | A2M | A2M-AS1 | A2ML1 | A2MP1 | A3GALT2 | A4GALT | A4GNT | AAAS | AACS | AACSP1 | AADAC | AADACL2 | AADACL2-AS1 | AADACL3 | AADACL4 | AADACP1 | AADAT | AAGAB | AAK1 | AAMDC | AAMP | AANAT | AAR2 | AARD | AARS1 | AARS2 | AARSD1 | AASDH | AASDHPPT | AASS | AATBC | AATF | AATK | ABALON | ABAT | ABCA1 | ABCA10 | ABCA11P | ABCA12 | ABCA13 | ABCA17P | ABCA2 | ABCA3 | ABCA4 | ABCA5 | ABCA6 | ABCA7 | ABCA8 | ABCA9 | ABCB1 | ABCB10 | ABCB11 | ABCB4 | ABCB5 | ABCB6 | ABCB7 | ABCB8 | ABCB9 | ABCC1 | ABCC10 | ABCC11 | ABCC12 | ABCC13 | ABCC2 | ABCC3 | ABCC4 | ABCC5 | ABCC6 | ABCC6P1 | ABCC6P2 | ABCC8 | ABCC9 | ABCD1 | ABCD2 | ABCD3 | ABCD4 | ABCE1 | ABCF1 | ABCF1-DT | ABCF2 | ABCF3 | ABCG1 | ABCG2

Disease Target / Biomarker