Target Name: DHCR7
NCBI ID: G1717
Review Report on DHCR7 Target / Biomarker Content of Review Report on DHCR7 Target / Biomarker
DHCR7
Other Name(s): DHCR7_HUMAN | Sterol delta-7-reductase | Smith-Lemli-Opitz syndrome | 7-dehydrocholesterol reductase, transcript variant 2 | sterol reductase SR-2 | delta7-sterol reductase | DHCR7 variant 1 | D7SR | putative sterol reductase SR-2 | Delta7-sterol reductase | sterol delta-7-reductase | Delta-7-dehydrocholesterol reductase | 7-dehydrocholesterol reductase, transcript variant 1 | 7-dehydrocholesterol reductase | Sterol Delta(7)-reductase | Sterol reductase SR-2 | Putative sterol reductase SR-2 | DHCR7 variant 2 | delta-7-dehydrocholesterol reductase | SLOS | 7-DHC reductase

DHCR7: A Potential Drug Target and Biomarker

Dihu DHCR7 is a gene that encodes a protein known as heat shock protein 7 (Hsp7). Hsp7 is a cytoplasmic protein that is expressed in various cell types and is involved in various cellular processes, including stress response, protein folding, and cell signaling. DHCR7 has also been shown to play a role in the development and progression of various diseases, including cancer and neurodegenerative diseases.

Due to its involvement in a wide range of cellular processes, DHCR7 has potential as a drug target. By targeting DHCR7, researchers can potentially develop new treatments for a variety of diseases. Additionally, DHCR7 has also been shown to be a potential biomarker, which can be used to diagnose and monitor the progression of certain diseases.

One of the key challenges in developing new treatments for diseases is identifying the underlying causes of the disease and determining what factors contribute to its development. DHCR7 provides insight into the stress response pathway, which is a critical network that helps cells respond to stress and maintain cellular homeostasis. It is involved in the regulation of various cellular processes that are critical for cell survival, including the regulation of protein folding, stress signaling, and DNA damage repair.

Research has also shown that DHCR7 is involved in the development and progression of various diseases, including cancer and neurodegenerative diseases. For example, studies have shown that high levels of Hsp7 expression are associated with poor prognosis in patients with pancreatic cancer, and that Hsp7 levels are elevated in the brains of individuals with Alzheimer's disease.

In addition to its potential as a drug target and biomarker, DHCR7 also has potential as a therapeutic agent. By using small molecules or antibodies to target DHCR7, researchers can potentially reduce the production of Hsp7 and improve the body's ability to respond to stress and maintain cellular homeostasis. This could lead to a variety of potential therapeutic applications, including the treatment of chronic diseases and injuries.

Targeting DHCR7 also has the potential to be a highly effective and efficient way to diagnose and monitor the progression of certain diseases. By using antibodies or small molecules to target DHCR7, researchers can potentially detect the disease at an early stage and monitor its progression over time. This could lead to earlier treatment and improved outcomes for patients.

In conclusion, DHCR7 is a gene that encodes a protein involved in various cellular processes and has the potential as a drug target and biomarker. Its involvement in the stress response pathway and its association with the development and progression of various diseases make it an attractive target for research and therapeutic development. Further research is needed to fully understand the role of DHCR7 in disease and to develop effective treatments.

Protein Name: 7-dehydrocholesterol Reductase

Functions: 7-dehydrocholesterol reductase of the cholesterol biosynthetic pathway reducing the C7-C8 double bond of cholesta-5,7-dien-3beta-ol (7-dehydrocholesterol/7-DHC) and cholesta-5,7,24-trien-3beta-ol, two intermediates in that pathway

The "DHCR7 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about DHCR7 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

DHDDS | DHDDS-AS1 | DHDH | DHFR | DHFR2 | DHFRP3 | DHH | DHODH | DHPS | DHRS1 | DHRS11 | DHRS12 | DHRS13 | DHRS2 | DHRS3 | DHRS4 | DHRS4-AS1 | DHRS4L1 | DHRS4L2 | DHRS7 | DHRS7B | DHRS7C | DHRS9 | DHRSX | DHTKD1 | DHX15 | DHX16 | DHX29 | DHX30 | DHX32 | DHX33 | DHX34 | DHX35 | DHX36 | DHX37 | DHX38 | DHX40 | DHX57 | DHX58 | DHX8 | DHX9 | DIABLO | Diacylglycerol Acyltransferase (DGAT) | Diacylglycerol kinase | DIAPH1 | DIAPH2 | DIAPH3 | DIAPH3-AS1 | DICER1 | DICER1-AS1 | Dickkopf protein | DIDO1 | DiGeorge syndrome critical region gene 9 | Dimethylaniline monooxygenase [N-oxide-forming] | DIMT1 | DINOL | DIO1 | DIO2 | DIO2-AS1 | DIO3 | DIO3OS | DIP2A | DIP2A-IT1 | DIP2B | DIP2C | DIP2C-AS1 | Dipeptidase | Dipeptidyl-Peptidase | DIPK1A | DIPK1B | DIPK1C | DIPK2A | DIPK2B | DIRAS1 | DIRAS2 | DIRAS3 | DIRC1 | DIRC3 | DIRC3-AS1 | DIS3 | DIS3L | DIS3L2 | DISC1 | DISC1FP1 | DISC2 | Disintegrin and Metalloproteinase domain-containing protein (ADAM) (nospecified subtype) | DISP1 | DISP2 | DISP3 | DIXDC1 | DKC1 | DKFZp434L192 | DKFZp451A211 | DKFZp451B082 | DKFZP586I1420 | DKK1 | DKK2 | DKK3 | DKK4 | DKKL1