Target Name: DNM1
NCBI ID: G1759
Review Report on DNM1 Target / Biomarker Content of Review Report on DNM1 Target / Biomarker
DNM1
Other Name(s): DYN1_HUMAN | DNM | Dynamin 1, transcript variant 1 | dynamin 1 | Dynamin-1 | DNM1 variant 1 | Dynamin 1 | DEE31 | Dynamin GTPase | EIEE31

DNM1: A Drug Target / Disease Biomarker

DNM1, also known as Dnm1, is a protein that is expressed in various tissues throughout the body, including the brain, muscle, liver, and pancreas. It is a key regulator of the cell cycle, which is the process by which cells grow, divide, and replicate their genetic material. Dnm1 is also involved in the development and maintenance of neural stem cells, which are a type of cell that can give rise to a variety of tissues and organs in the body.

Recent studies have suggested that Dnm1 may be a drug target or biomarker for a variety of diseases, including cancer, neurodegenerative diseases, and developmental disorders. This is because Dnm1 is known to play a role in the regulation of cell growth and division, which is often disrupted in these conditions.

One potential mechanism by which Dnm1 may be targeted by drugs is by inhibiting its activity in the cell cycle. The cell cycle is a critical process that allows cells to grow and divide, and it is often hyperactive in cancer cells. By inhibiting Dnm1's activity in the cell cycle, drugs may be able to disrupt the growth and proliferation of cancer cells.

Another potential mechanism by which Dnm1 may be targeted by drugs is by disrupting its role in the development and maintenance of neural stem cells. Neural stem cells are a type of cell that have the ability to give rise to a variety of tissues and organs in the body, and they are often found in the brain, spinal cord, and pancreas. Dnm1 is known to play a role in the regulation of neural stem cell proliferation and differentiation, and it is thought to be involved in the development of various neurological and psychiatric disorders. By disrupting Dnm1's activity in these processes, drugs may be able to treat conditions such as Alzheimer's disease, Parkinson's disease, and schizophrenia.

In addition to its potential as a drug target or biomarker, Dnm1 is also of interest as a potential therapeutic agent for a variety of other conditions. For example, Dnm1 has been shown to be involved in the regulation of the blood-brain barrier, which is the barrier that separates the brain from the rest of the body and helps to protect it from harmful substances. By manipulating the blood-brain barrier, drugs may be able to deliver drugs to the brain more effectively and potentially treat conditions such as Alzheimer's disease and Parkinson's disease.

Overall, Dnm1 is a protein that is expressed in various tissues throughout the body and is involved in the regulation of cell growth, division, and the development and maintenance of neural stem cells. Its potential as a drug target or biomarker for a variety of diseases makes it an attractive target for further research and development.

Protein Name: Dynamin 1

Functions: Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. Involved in receptor-mediated endocytosis

The "DNM1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about DNM1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

DNM1L | DNM1P33 | DNM1P35 | DNM1P41 | DNM1P46 | DNM1P49 | DNM2 | DNM3 | DNM3OS | DNMBP | DNMBP-AS1 | DNMT1 | DNMT1-G9a-PCNA complex | DNMT1-HDAC2-DMAP1 complex | DNMT1-Rb-E2F1-HDAC1 complex | DNMT3A | DNMT3AP1 | DNMT3B | DNMT3L | DNPEP | DNPH1 | DNTT | DNTTIP1 | DNTTIP2 | DOC2A | DOC2B | DOC2GP | DOCK1 | DOCK10 | DOCK11 | DOCK2 | DOCK3 | DOCK4 | DOCK4-AS1 | DOCK5 | DOCK6 | DOCK7 | DOCK8 | DOCK8-AS1 | DOCK9 | DOCK9-DT | DOHH | DOK1 | DOK2 | DOK3 | DOK4 | DOK5 | DOK6 | DOK7 | Dolichol-phosphate-mannose synthase complex | DOLK | DOLPP1 | DONSON | DOP1A | DOP1B | Dopamine receptor | DOT1L | Double homeobox protein 4 | DP2-E2F4 complex | DPAGT1 | DPCD | DPEP1 | DPEP2 | DPEP3 | DPF1 | DPF2 | DPF3 | DPH1 | DPH2 | DPH3 | DPH3P1 | DPH5 | DPH5-DT | DPH6 | DPH6-DT | DPH7 | DPM1 | DPM2 | DPM3 | DPP10 | DPP10-AS1 | DPP3 | DPP3-DT | DPP4 | DPP6 | DPP7 | DPP8 | DPP9 | DPP9-AS1 | DPPA2 | DPPA2P3 | DPPA3 | DPPA3P1 | DPPA3P2 | DPPA4 | DPPA4P3 | DPPA5 | DPPA5P4 | DPRX | DPRXP2