Understanding DOHH_HUMAN: A Potential Drug Target (G83475)

Target Name: DOHH

NCBI ID: G83475

DOHH

Understanding DOHH_HUMAN: A Potential Drug Target

The Department of Health and Human Services (DOHH) is a vital part of the government that is responsible for overseeing the health and well-being of the American people. One of the many important functions of the DOHH is to fund and support research to develop new treatments and therapies for diseases and conditions. This work is carried out by the National Institutes of Health (NIH), which is a part of the DOHH.

One area of research that has seen significant progress in recent years is the study of drug targets and biomarkers. Drug targets are molecules that are associated with the development and progression of a particular disease. Biomarkers are molecules that are produced by the body that can be used as indicators of the presence of a particular disease or condition. The development of new drug targets and biomarkers has the potential to revolutionize the field of medicine and improve the treatment outcomes for many diseases.

One potential drug target that is being studied extensively is the protein known as DOHH_HUMAN. This protein is a key component of the DOHH and is involved in the regulation of a variety of cellular processes that are important for the health and well-being of the body.

The study of DOHH_HUMAN began in the late 1980s as part of a larger effort to understand the molecular mechanisms that regulate the growth and development of tissues. The protein was first identified in 1995 using a technique called mass spectrometry, which involves the separation and identification of molecules based on their mass.

Since its identification, significant research has been conducted to understand the role of DOHH_HUMAN in various cellular processes that are important for the health and well-being of the body. This research has led to a greater understanding of the underlying mechanisms that regulate cell growth, differentiation, and death, as well as the regulation of cellular signaling pathways that are important for many different cellular processes.

One of the key findings of this research is that DOHH_HUMAN plays a critical role in the regulation of cell death, also known as apoptosis. Apoptosis is a natural process that is important for the development and removal of damaged or dysfunctional cells in the body. However, when apoptosis is not properly regulated, it can lead to the development of a variety of diseases, including cancer, neurodegenerative diseases, and developmental disorders.

DOHH_HUMAN is involved in the regulation of apoptosis through its role in the transcription factor PAX1. PAX1 is a protein that is involved in the regulation of a wide range of cellular processes, including cell growth, differentiation, and apoptosis.

In addition to its role in apoptosis, DOHH_HUMAN is also involved in the regulation of many other cellular processes that are important for the health and well-being of the body. This includes the regulation of cell signaling pathways, the regulation of gene expression, and the regulation of cellular interactions with the surrounding environment.

The study of DOHH_HUMAN has significant implications for the development of new treatments and therapies for a wide range of diseases. By understanding the role of this protein in cellular processes, researchers are able to identify new targets for drug development and develop new approaches for treating a variety of diseases.

In conclusion, the protein known as DOHH_HUMAN is a key component of the Department of Health and Human Services and has significant implications for the development of new treatments and therapies for a wide range of diseases. Further research is needed to fully understand the role of this protein in cellular processes and its potential as a drug target.

Protein Name: Deoxyhypusine Hydroxylase

Functions: Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate produced by deoxyhypusine synthase/DHPS on a critical lysine of the eukaryotic translation initiation factor 5A/eIF-5A. This is the second step of the post-translational modification of that lysine into an unusual amino acid residue named hypusine (PubMed:16533814, PubMed:16371467, PubMed:19706422). Hypusination is unique to mature eIF-5A factor and is essential for its function (By similarity)

The "DOHH Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about DOHH comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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