Target Name: DPF3
NCBI ID: G8110
Review Report on DPF3 Target / Biomarker Content of Review Report on DPF3 Target / Biomarker
DPF3
Other Name(s): Cer-d4 | Zinc finger protein DPF3 (isoform 1) | 2810403B03Rik | Double PHD fingers 3 | SMARCG3 | CERD4 | DPF3_HUMAN | Cer-d4 homolog | Zinc finger protein cer-d4 | zinc finger protein cer-d4 | BAF45C | double PHD fingers 3 | DPF3 variant 1 | FLJ14079 | Zinc finger protein DPF3 | BRG1-associated factor 45C | D4, zinc and double PHD fingers, family 3

DPF3: A Potential Drug Target and Biomarker

DPF3 (cer-d4) is a protein that is expressed in various tissues throughout the body, including the brain, heart, and kidneys. It is a key regulator of the development and maintenance of blood vessels, and is involved in a number of important cellular processes that maintain tissue health.

DPF3 is a member of the transforming growth factor family, which includes a group of proteins that are involved in the regulation of cell growth, differentiation, and survival. These proteins are known as TGF-β family proteins, and they play a crucial role in the development and maintenance of tissues and organs.

DPF3 is involved in a number of different processes in the body, including the regulation of angiogenesis, the formation of blood vessels, and the maintenance of tissue repair. It is a key regulator of the smooth muscle contractions that are necessary for maintaining blood pressure, and it is involved in the regulation of the blood flow to the brain.

DPF3 is also involved in the regulation of stem cell proliferation and differentiation. It is a key regulator of the stem cell niche, and it is involved in the decision of stem cells to differentiate into different cell types.

DPF3 is a protein that has the potential to be a drug target or biomarker. Its involvement in a number of important cellular processes makes it an attractive target for researchers to study, and its potential functions as a drug or biomarker make it an important area of research.

DPF3 has been shown to play a role in a number of diseases, including cancer, cardiovascular disease, and neurodegenerative diseases. It is involved in the regulation of angiogenesis, the formation of blood vessels, and the maintenance of tissue repair, and its dysfunction has been implicated in a number of these diseases.

In addition, DFP3 is also a good candidate for a biomarker for cancer, as it has been shown to be upregulated in a number of cancer types, including breast, lung, and ovarian cancer. This suggests that it may be a useful biomarker for monitoring the progression of these diseases and for identifying potential therapeutic targets.

DPF3 is also a good candidate for a drug target because of its involvement in the regulation of cellular processes that are important for the development and maintenance of tissues and organs. Its dysfunction has been implicated in a number of diseases, including cancer, cardiovascular disease, and neurodegenerative diseases.

In addition, DFP3 is also involved in the regulation of stem cell proliferation and differentiation, which makes it an attractive target for drugs that are aimed at treating these conditions.

Overall, DPF3 is a protein that has the potential to be a drug target or biomarker. Its involvement in a number of important cellular processes makes it an attractive target for researchers to study, and its potential functions as a drug or biomarker make it an important area of research. Further studies are needed to fully understand its role in these processes and to determine its potential as a drug or biomarker.

Protein Name: Double PHD Fingers 3

Functions: Belongs to the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity). Muscle-specific component of the BAF complex, a multiprotein complex involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Specifically binds acetylated lysines on histone 3 and 4 (H3K14ac, H3K9ac, H4K5ac, H4K8ac, H4K12ac, H4K16ac). In the complex, it acts as a tissue-specific anchor between histone acetylations and methylations and chromatin remodeling. It thereby probably plays an essential role in heart and skeletal muscle development

The "DPF3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about DPF3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

DPH1 | DPH2 | DPH3 | DPH3P1 | DPH5 | DPH5-DT | DPH6 | DPH6-DT | DPH7 | DPM1 | DPM2 | DPM3 | DPP10 | DPP10-AS1 | DPP3 | DPP3-DT | DPP4 | DPP6 | DPP7 | DPP8 | DPP9 | DPP9-AS1 | DPPA2 | DPPA2P3 | DPPA3 | DPPA3P1 | DPPA3P2 | DPPA4 | DPPA4P3 | DPPA5 | DPPA5P4 | DPRX | DPRXP2 | DPRXP4 | DPT | DPY19L1 | DPY19L1P1 | DPY19L2 | DPY19L2P1 | DPY19L2P2 | DPY19L2P3 | DPY19L2P4 | DPY19L3 | DPY19L3-DT | DPY19L4 | DPY30 | DPYD | DPYD-AS1 | DPYS | DPYSL2 | DPYSL3 | DPYSL4 | DPYSL5 | DQX1 | DR1 | DRAIC | DRAM1 | DRAM2 | DRAP1 | DRAXIN | DRB sensitivity-inducing factor complex | DRC1 | DRC3 | DRC7 | DRD1 | DRD2 | DRD3 | DRD4 | DRD5 | DRD5P1 | DRD5P2 | DRG1 | DRG2 | DRGX | DRICH1 | DROSHA | DRP2 | DSC1 | DSC2 | DSC3 | DSCAM | DSCAM-AS1 | DSCAML1 | DSCC1 | DSCR10 | DSCR4 | DSCR8 | DSCR9 | DSE | DSEL | DSEL-AS1 | DSG1 | DSG1-AS1 | DSG2 | DSG3 | DSG4 | DSN1 | DSP | DSP-AS1 | DSPP