Target Name: DPF1
NCBI ID: G8193
Review Report on DPF1 Target / Biomarker Content of Review Report on DPF1 Target / Biomarker
DPF1
Other Name(s): D4, zinc and double PHD fingers family 1 | double PHD fingers 1 | DPF1_HUMAN | neuro-d4 | Neuro-d4 homolog | NEUD4 | BAF45B | SMARCG1 | Zinc finger protein neuro-d4 | neuro-d4 homolog | Double PHD fingers 1 | DPF1 variant 1 | BAF45b | BRG1-associated factor 45B | Zinc finger protein neuro-d4 isoform a

DPF1: A Potential Drug Target for Cancer

DPF1 (D4, zinc and double PHD fingers family 1) is a gene that encodes a protein known as df1, which is involved in a variety of cellular processes. One of the most promising aspects of df1 is its potential as a drug target or biomarker.

The protein encoded by df1 is involved in the process of cell division, specifically mitosis. During mitosis, the cell divides and the chromosome is replicated, ensuring that the cell has a complete set of genetic information. df1 plays a crucial role in this process by helping to maintain the integrity of the chromatin during cell division.

One of the key functions of df1 is its ability to interact with the DNA double helix. This interaction is important for the regulation of gene expression and the development of cancer. Studies have shown that df1 can interact with the double helix in a variety of ways , including through the formation of a complex with DNA-protein complexes.

In addition to its role in cell division and DNA interaction, df1 has also been shown to play a role in the regulation of cellular processes that are important for cancer development. For example, studies have shown that df1 can be involved in the regulation of cell adhesion, a process that is important for the development of cancer stem cells.

The potential drug target for df1 is based on its involvement in the regulation of cell division and its ability to interact with the DNA double helix. Drugs that target df1 have the potential to inhibit its activity and disrupt its role in cell division and DNA interaction. This could lead to a variety of potential therapeutic benefits, including the treatment of cancer.

In addition to its potential as a drug target, df1 has also been shown to be a potential biomarker for cancer. The df1 gene has been shown to be expressed in a variety of tissues and cells, including cancer cells. This suggests that df1 may be a useful biomarker for the diagnosis and treatment of cancer.

The identification of df1 as a potential drug target or biomarker has significant implications for the development of new therapies for cancer. By targeting df1 with small molecules or other therapeutic agents, researchers may be able to disrupt its activity and achieve a variety of therapeutic benefits.

In conclusion, DPF1 (D4, zinc and double PHD fingers family 1) is a gene that encodes a protein involved in the regulation of cell division and DNA interaction. Its potential as a drug target or biomarker makes it an attractive target for the development of new therapies for cancer. Further research is needed to fully understand the role of df1 in cell biology and its potential as a therapeutic agent.

Protein Name: Double PHD Fingers 1

Functions: May have an important role in developing neurons by participating in regulation of cell survival, possibly as a neurospecific transcription factor. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to postmitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity)

The "DPF1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about DPF1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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DPF2 | DPF3 | DPH1 | DPH2 | DPH3 | DPH3P1 | DPH5 | DPH5-DT | DPH6 | DPH6-DT | DPH7 | DPM1 | DPM2 | DPM3 | DPP10 | DPP10-AS1 | DPP3 | DPP3-DT | DPP4 | DPP6 | DPP7 | DPP8 | DPP9 | DPP9-AS1 | DPPA2 | DPPA2P3 | DPPA3 | DPPA3P1 | DPPA3P2 | DPPA4 | DPPA4P3 | DPPA5 | DPPA5P4 | DPRX | DPRXP2 | DPRXP4 | DPT | DPY19L1 | DPY19L1P1 | DPY19L2 | DPY19L2P1 | DPY19L2P2 | DPY19L2P3 | DPY19L2P4 | DPY19L3 | DPY19L3-DT | DPY19L4 | DPY30 | DPYD | DPYD-AS1 | DPYS | DPYSL2 | DPYSL3 | DPYSL4 | DPYSL5 | DQX1 | DR1 | DRAIC | DRAM1 | DRAM2 | DRAP1 | DRAXIN | DRB sensitivity-inducing factor complex | DRC1 | DRC3 | DRC7 | DRD1 | DRD2 | DRD3 | DRD4 | DRD5 | DRD5P1 | DRD5P2 | DRG1 | DRG2 | DRGX | DRICH1 | DROSHA | DRP2 | DSC1 | DSC2 | DSC3 | DSCAM | DSCAM-AS1 | DSCAML1 | DSCC1 | DSCR10 | DSCR4 | DSCR8 | DSCR9 | DSE | DSEL | DSEL-AS1 | DSG1 | DSG1-AS1 | DSG2 | DSG3 | DSG4 | DSN1 | DSP