Target Name: DOK6
NCBI ID: G220164
Review Report on DOK6 Target / Biomarker Content of Review Report on DOK6 Target / Biomarker
DOK6
Other Name(s): HsT3226 | Downstream of tyrosine kinase 6 | docking protein 6 | downstream of tyrosine kinase 6 | MGC20785 | DOK5L | Docking protein 6 | DOK6_HUMAN

DOK6: A Protein Involved in Brain Function and Drug Targets

DOK6 (HsT3226) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a key regulator of the blood-brain barrier, which is responsible for controlling the movement of molecules into and out of the brain.

One of the things that makes DOK6 so interesting as a drug target is its role in the regulation of blood-brain barrier function. The blood-brain barrier is a specialized barrier that separates the brain from the rest of the body, and it is designed to protect the brain from harmful substances. However, this barrier can also prevent important nutrients and medications from reaching the brain.

DOK6 plays a key role in breaking down the blood-brain barrier and allowing nutrients and medications to reach the brain. This is important for maintaining the health and function of the brain, and for treating various neurological disorders.

In addition to its role in the blood-brain barrier, DOK6 is also a potential biomarker for certain diseases. For example, studies have shown that DOK6 levels are elevated in the brains of individuals with Alzheimer's disease, which is a degenerative brain disorder that is characterized by memory loss and other cognitive impairments.

DOK6 may also be a potential drug target for certain conditions. For example, some studies have suggested that DOK6 may be involved in the development and progression of certain types of cancer, such as breast cancer. Additionally, DOK6 levels have been shown to be elevated in the blood of individuals with certain types of cancer, which may make it an attractive target for cancer treatments.

Overall, DOK6 is a protein that is involved in a wide range of physiological processes in the body. Its role in the regulation of blood-brain barrier function and its potential as a drug target make it an interesting candidate for further research and development.

Protein Name: Docking Protein 6

Functions: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK6 promotes Ret-mediated neurite growth. May have a role in brain development and/or maintenance

The "DOK6 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about DOK6 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

DOK7 | Dolichol-phosphate-mannose synthase complex | DOLK | DOLPP1 | DONSON | DOP1A | DOP1B | Dopamine receptor | DOT1L | Double homeobox protein 4 | DP2-E2F4 complex | DPAGT1 | DPCD | DPEP1 | DPEP2 | DPEP3 | DPF1 | DPF2 | DPF3 | DPH1 | DPH2 | DPH3 | DPH3P1 | DPH5 | DPH5-DT | DPH6 | DPH6-DT | DPH7 | DPM1 | DPM2 | DPM3 | DPP10 | DPP10-AS1 | DPP3 | DPP3-DT | DPP4 | DPP6 | DPP7 | DPP8 | DPP9 | DPP9-AS1 | DPPA2 | DPPA2P3 | DPPA3 | DPPA3P1 | DPPA3P2 | DPPA4 | DPPA4P3 | DPPA5 | DPPA5P4 | DPRX | DPRXP2 | DPRXP4 | DPT | DPY19L1 | DPY19L1P1 | DPY19L2 | DPY19L2P1 | DPY19L2P2 | DPY19L2P3 | DPY19L2P4 | DPY19L3 | DPY19L3-DT | DPY19L4 | DPY30 | DPYD | DPYD-AS1 | DPYS | DPYSL2 | DPYSL3 | DPYSL4 | DPYSL5 | DQX1 | DR1 | DRAIC | DRAM1 | DRAM2 | DRAP1 | DRAXIN | DRB sensitivity-inducing factor complex | DRC1 | DRC3 | DRC7 | DRD1 | DRD2 | DRD3 | DRD4 | DRD5 | DRD5P1 | DRD5P2 | DRG1 | DRG2 | DRGX | DRICH1 | DROSHA | DRP2 | DSC1 | DSC2 | DSC3 | DSCAM