DPF2: Key Regulator of DNA Damage Repair and Cell Growth (G5977)
DPF2: Key Regulator of DNA Damage Repair and Cell Growth
DPF2 (Protein Requiem) is a protein that is expressed in various tissues throughout the body, including the brain, heart, and kidneys. It is a key regulator of the DNA damage repair pathway, which is involved in ensuring that damaged DNA is repaired and degraded properly to prevent the development of cancer.
DPF2 is a protein that is known for its role in preventing DNA damage and repair. It is a key regulator of the DNA damage repair pathway, which is involved in ensuring that damaged DNA is repaired and degraded properly to prevent the development of cancer.
One of the key functions of DPF2 is its role in preventing DNA double-strand breaks, which are a common type of damage to DNA that can occur during the repair process. Double-strand breaks can occur due to a variety of factors, including exposure to radiation, chemicals, or other forms of stress.
DPF2 helps to ensure that these types of breaks are repaired by the body's immune system. It does this by helping to recruit a group of immune cells called T cells to the site of the double-strand break. Once there, T cells help to stimulate an immune response, which leads to the formation of a specialized immune cell called a T-cell memory clone. This cell is responsible for repairing the double-strand break and ensuring that the DNA is fully repaired.
In addition to its role in preventing DNA double-strand breaks, DPF2 is also involved in regulating the growth and division of cells. It helps to ensure that cells are able to divide and grow in a controlled and orderly manner, and it also helps to prevent the formation of cancerous mutations.
DPF2 is a protein that is known for its role in preventing DNA damage and repair. It is a key regulator of the DNA damage repair pathway, which is involved in ensuring that damaged DNA is repaired and degraded properly to prevent the development of cancer.
In conclusion, DPF2 is a protein that plays a critical role in ensuring that the body's cells are able to repair and divide properly. It is involved in preventing DNA double-strand breaks and in regulating the growth and division of cells. As a result, it is a potential drug target and a biomarker for a variety of diseases, including cancer.
Protein Name: Double PHD Fingers 2
Functions: Plays an active role in transcriptional regulation by binding modified histones H3 and H4 (PubMed:28533407, PubMed:27775714). Is a negative regulator of myeloid differentiation of hematopoietic progenitor cells (PubMed:28533407). Might also have a role in the development and maturation of lymphoid cells (By similarity). Involved in the regulation of non-canonical NF-kappa-B pathway (PubMed:20460684)
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• general information;
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• expression level;
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• drug resistance;
• related combination drugs;
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More Common Targets
DPF3 | DPH1 | DPH2 | DPH3 | DPH3P1 | DPH5 | DPH5-DT | DPH6 | DPH6-DT | DPH7 | DPM1 | DPM2 | DPM3 | DPP10 | DPP10-AS1 | DPP3 | DPP3-DT | DPP4 | DPP6 | DPP7 | DPP8 | DPP9 | DPP9-AS1 | DPPA2 | DPPA2P3 | DPPA3 | DPPA3P1 | DPPA3P2 | DPPA4 | DPPA4P3 | DPPA5 | DPPA5P4 | DPRX | DPRXP2 | DPRXP4 | DPT | DPY19L1 | DPY19L1P1 | DPY19L2 | DPY19L2P1 | DPY19L2P2 | DPY19L2P3 | DPY19L2P4 | DPY19L3 | DPY19L3-DT | DPY19L4 | DPY30 | DPYD | DPYD-AS1 | DPYS | DPYSL2 | DPYSL3 | DPYSL4 | DPYSL5 | DQX1 | DR1 | DRAIC | DRAM1 | DRAM2 | DRAP1 | DRAXIN | DRB sensitivity-inducing factor complex | DRC1 | DRC3 | DRC7 | DRD1 | DRD2 | DRD3 | DRD4 | DRD5 | DRD5P1 | DRD5P2 | DRG1 | DRG2 | DRGX | DRICH1 | DROSHA | DRP2 | DSC1 | DSC2 | DSC3 | DSCAM | DSCAM-AS1 | DSCAML1 | DSCC1 | DSCR10 | DSCR4 | DSCR8 | DSCR9 | DSE | DSEL | DSEL-AS1 | DSG1 | DSG1-AS1 | DSG2 | DSG3 | DSG4 | DSN1 | DSP | DSP-AS1
