DOCK4 as A Potential Drug Target and Biomarker for Diseases (G9732)

Target Name: DOCK4

NCBI ID: G9732

DOCK4

DOCK4 as A Potential Drug Target and Biomarker for Diseases

DOCK4 (D hydrophobic channel 4) is a gene that encodes a protein known as DOCK4, which is a key regulator of cell-cell adhesion. The DOCK4 protein plays a crucial role in the development and maintenance of tissues such as the skin, heart, and brain, and is involved in various cellular processes, including cell signaling, migration, and the regulation of cell-cell adhesion.

Recent studies have identified DOCK4 as a potential drug target for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. This has led to a growing interest in the research of DOCK4 and its potential as a therapeutic approach.

DOCK4 as a drug target

DOCK4 has been identified as a potential drug target due to its involvement in various cellular processes that are crucial for disease development. One of the main reasons for its potential as a drug target is its involvement in cell-cell adhesion. DOCK4 plays a role in regulates the formation and maintenance of tight junctions, which are a type of cell-cell adhesion that is essential for various physiological processes, including cell signaling and tissue structure.

DOCK4 has also been shown to be involved in the regulation of cell migration, which is a critical process for the development and maintenance of tissues and organs. In addition, DOCK4 has been linked to various neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. This has led to the speculation that DOCK4 may be a potential drug target for these diseases.

Another potential mechanism by which DOCK4 may be targeted as a drug is its involvement in the regulation of cell signaling. DOCK4 has been shown to play a role in the regulation of various signaling pathways, including the TGF-β pathway. This pathway is involved in the regulation of cell growth, differentiation, and survival, and is a key factor in the development and maintenance of tissues.

DOCK4 as a biomarker

In addition to its potential as a drug target, DOCK4 has also been identified as a potential biomarker for various diseases. One of the main reasons for its potential as a biomarker is its involvement in the regulation of cell-cell adhesion. This has led to the assumption that DOCK4 may be used as a biomarker for diseases that are characterized by changes in cell-cell adhesion, such as cancer.

In addition, DOCK4 has been shown to be involved in the regulation of cell signaling, which is a critical process for the development and maintenance of tissues. This has led to the assumption that DOCK4 may be used as a biomarker for diseases that are characterized by changes in cellular signaling, such as neurodegenerative diseases.

Conclusion

DOCK4 is a gene that encodes a protein that plays a crucial role in the development and maintenance of tissues. Its involvement in various cellular processes, including cell signaling and cell-cell adhesion, makes it a potential drug target for various diseases. In addition, DOCK4 has been identified as a potential biomarker for various diseases, including cancer and neurodegenerative diseases. Further research is needed to fully understand the role of DOCK4 in these diseases and to develop effective therapies that target DOCK4.

Protein Name: Dedicator Of Cytokinesis 4

Functions: Functions as a guanine nucleotide exchange factor (GEF) that promotes the exchange of GDP to GTP, converting inactive GDP-bound small GTPases into their active GTP-bound form (PubMed:12628187, PubMed:16464467). Involved in regulation of adherens junction between cells (PubMed:12628187). Plays a role in cell migration (PubMed:20679435)

The "DOCK4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about DOCK4 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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