Target Name: PDZRN3
NCBI ID: G23024
Review Report on PDZRN3 Target / Biomarker Content of Review Report on PDZRN3 Target / Biomarker
PDZRN3
Other Name(s): KIAA1095 | PDZ domain containing ring finger 3, transcript variant 1 | SEMACAP3 | Protein SEMACAP3 | PZRN3_HUMAN | PDZ domain containing ring finger 3 | Ligand of Numb protein X 3 | Likely ortholog of mouse semaF cytoplasmic domain associated protein 3 | likely ortholog of mouse semaF cytoplasmic domain associated protein 3 | OTTHUMP00000213615 | PDZRN3 variant 1 | ligand of Numb protein X 3 | SEMCAP3 | Semaphorin cytoplasmic domain-associated protein 3 | PDZ domain-containing RING finger protein 3 | OTTHUMP00000213617 | semaphorin cytoplasmic domain-associated protein 3 | LNX3 | RING-type E3 ubiquitin transferase PDZRN3 | E3 ubiquitin-protein ligase PDZRN3 | OTTHUMP00000213618 | OTTHUMP00000213613 | E3 ubiquitin-protein ligase PDZRN3 (isoform 1) | OTTHUMP00000213616

PDZRN3: Regulating Zinc Levels and Cell Processes

PDZRN3 (Proteasome-RegulatedZinc-Nuclear Protein 3) is a protein that is expressed in almost all human tissues and is involved in the regulation of protein synthesis and degradation. It is also known as KIAA1095 and has been identified as a potential drug target and biomarker.

PDZRN3 is a key protein that is involved in the regulation of the proteasome, which is a complex protein that helps to break down and remove proteins from the cell. The proteasome is responsible for removing damaged or unnecessary proteins, and it is a key mechanism for maintaining the stability and integrity of the cell.

PDZRN3 is a 24-kDa protein that is expressed in a variety of tissues, including muscle, bone, liver, and pancreas. It is primarily localized to the nuclei of these tissues and is involved in the regulation of protein synthesis and degradation.

One of the key functions of PDZRN3 is to regulate the levels of zinc in the cell. Zinc is an essential metal that plays a variety of roles in the cell, including signaling, DNA replication, and cell growth. PDZRN3 helps to regulate the levels of zinc in the cell by controlling the entry of zinc into the nucleus.

PDZRN3 is also involved in the regulation of gene expression. It has been shown to play a role in the regulation of several gene expression pathways, including the TGF-β pathway, the Wnt pathway, and the Hedgehog pathway.

PDZRN3 has also been shown to be involved in the regulation of cellular signaling pathways. It has been shown to play a role in the regulation of several signaling pathways, including the PI3K/Akt signaling pathway and the NF-kappa-B signaling pathway.

PDZRN3 is also involved in the regulation of cellular stress responses. It has been shown to play a role in the regulation of cellular stress responses, including the response to oxidative stress and the response to thermal stress.

PDZRN3 has been shown to be involved in the regulation of cellular repair processes. It has been shown to play a role in the regulation of cellular repair processes, including the repair of DNA damage and the regulation of the DNA damage response.

PDZRN3 is also involved in the regulation of the cell cycle. It has been shown to play a role in the regulation of the cell cycle, including the G1 phase and the S phase of the cell cycle.

PDZRN3 is also involved in the regulation of the cytoskeleton. It has been shown to play a role in the regulation of the cytoskeleton, including the stability of the microtubules in the

Protein Name: PDZ Domain Containing Ring Finger 3

Functions: E3 ubiquitin-protein ligase. Plays an important role in regulating the surface level of MUSK on myotubes. Mediates the ubiquitination of MUSK, promoting its endocytosis and lysosomal degradation. Might contribute to terminal myogenic differentiation

The "PDZRN3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PDZRN3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

PDZRN3-AS1 | PDZRN4 | PEA15 | PEAK1 | PEAK3 | PEAR1 | PeBoW complex | PEBP1 | PEBP1P2 | PEBP4 | PECAM1 | PECR | PEDS1 | PEDS1-UBE2V1 | PEF1 | PEG10 | PEG13 | PEG3 | PEG3-AS1 | PELATON | PELI1 | PELI2 | PELI3 | PELO | PELP1 | PELP1-DT | PEMT | PENK | PENK-AS1 | PEPD | Peptidyl arginine deiminase (PAD) | Peptidylprolyl Isomerase | PER1 | PER2 | PER3 | PER3P1 | PERM1 | Peroxiredoxin | Peroxisome Proliferator-Activated Receptors (PPAR) | PERP | PES1 | PET100 | PET117 | PEX1 | PEX10 | PEX11A | PEX11B | PEX11G | PEX12 | PEX13 | PEX14 | PEX16 | PEX19 | PEX2 | PEX26 | PEX3 | PEX5 | PEX5L | PEX5L-AS2 | PEX6 | PEX7 | PF4 | PF4V1 | PFAS | PFDN1 | PFDN2 | PFDN4 | PFDN5 | PFDN6 | PFKFB1 | PFKFB2 | PFKFB3 | PFKFB4 | PFKL | PFKM | PFKP | PFN1 | PFN1P2 | PFN1P3 | PFN1P4 | PFN1P6 | PFN1P8 | PFN2 | PFN3 | PFN4 | PGA3 | PGA4 | PGA5 | PGAM1 | PGAM1P5 | PGAM1P7 | PGAM1P8 | PGAM2 | PGAM4 | PGAM5 | PGAM5-KEAP1-NRF2 Complex | PGAP1 | PGAP2 | PGAP3 | PGAP4