PDS5A: A Potential Drug Target and Biomarker for Cancer (G23244)

Target Name: PDS5A

NCBI ID: G23244

PDS5A

PDS5A: A Potential Drug Target and Biomarker for Cancer

Chromatin is the complex of DNA, RNA, and proteins that make up the chromosomes in the nucleus of a cell. It is responsible for the storage of genetic information and the regulation of gene expression. Chromatin organization and dynamics are critical for the proper functioning of the cell, and alterations in these processes have been implicated in many diseases, including cancer. One of the key proteins that regulates chromatin organization and dynamics is PDS5A, a non-coding RNA molecule that has been identified as a potential drug target and biomarker for cancer.

PDS5A is a member of the Pds5A family, which includes several similar proteins that share a conserved catalytic core and a common N-terminus. These proteins are involved in the regulation of chromatin structure and dynamics, and are thought to play a role in the maintenance of chromosomal stability. PDS5A is expressed in most tissues and cells, and has been shown to play a role in the regulation of stem cell maintenance, proliferation, and differentiation.

In addition to its role in stem cell biology, PDS5A has also been shown to be involved in the regulation of a variety of cellular processes, including cell adhesion, migration, and the regulation of ion channels. It has been shown to play a role in the regulation of cell signaling pathways, including the TGF-β pathway, which is involved in cell growth, differentiation, and survival.

PDS5A has also been shown to be involved in the regulation of gene expression. It has been shown to interact with several transcription factors, including TGF-β, NF1, and MBP, and has been shown to play a role in the regulation of gene expression in a variety of tissues and cells.

In addition to its role in gene expression, PDS5A has also been shown to be involved in the regulation of DNA replication. It has been shown to interact with the enzyme responsible for DNA replication, named DNRT1, and has been shown to play a role in the regulation of DNA replication in a variety of tissues and cells.

PDS5A has also been shown to be involved in the regulation of cell signaling pathways that are involved in cell death and stress. It has been shown to play a role in the regulation of cell apoptosis, which is the process by which cells undergo programmed cell death in response to environmental stressors, such as exposure to chemotherapy drugs.

In addition to its role in cell signaling pathways, PDS5A has also been shown to be involved in the regulation of tissue repair and regeneration. It has been shown to play a role in the regulation of tissue repair and regeneration in a variety of tissues and cells, including the regulation of wound healing and the regeneration of damaged tissues after injury.

Given the complexity of PDS5A's role in regulating chromatin structure and dynamics, as well as its involvement in a variety of cellular processes, it is a promising candidate for drug targeting. Several studies have shown that PDS5A can be targeted with small molecules, and that these treatments can have a variety of different effects on cellular behavior, including the regulation of stem cell maintenance, proliferation, and differentiation. In addition, several studies have also shown that targeting PDS5A with small molecules can have a variety of different effects on cancer biology, including the inhibition of cell growth, the inhibition of cancer cell migration, and the inhibition of cancer cell invasion and metastasis.

Overall, PDS5A is a non-coding RNA molecule that has been shown to play a variety of roles in cellular biology, including the regulation of stem cell maintenance, proliferation, and differentiation, as well as the regulation of DNA replication, gene expression, cell signaling pathways, tissue repair and regeneration. Given its complex role in these processes, PDS5A is a promising candidate for drug targeting, and further research is needed to fully understand its mechanisms of action and its potential as a drug target

Protein Name: PDS5 Cohesin Associated Factor A

Functions: Probable regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. May couple sister chromatid cohesion during mitosis to DNA replication. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair

The "PDS5A Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PDS5A comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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