Target Name: PDLIM3
NCBI ID: G27295
Review Report on PDLIM3 Target / Biomarker Content of Review Report on PDLIM3 Target / Biomarker
PDLIM3
Other Name(s): DKFZp686L0362 | Actinin-associated LIM protein | PDZ and LIM domain protein 3 | Alpha-actinin-2-associated LIM protein | alpha-actinin-2-associated LIM protein | PDZ and LIM domain protein 3 (isoform a) | PDLIM3 variant 1 | enigma homolog | PDZ and LIM domain 3 | ALP | Enigma homolog | PDLI3_HUMAN

PDLIM3: A Unique Protein with Potential as A Drug and Biomarker

PDLIM3 (padding-layer interprotein domain-containing protein 3) is a protein that is expressed in various tissues of the human body, including the brain, heart, and kidneys. It is a member of the interprotein domain family, which is a common structural domain found in proteins that regulate various cellular processes.

PDLIM3 is unique due to its structure and function. It has a unique N-terminus that is rich in positively charged amino acids, which is known as a \"padding layer.\" This layer serves as a scaffold to help the protein fold into its three-dimensional structure, which is important for its function in cell signaling. Additionally, PDLIM3 has a unique C-terminus that is involved in protein-protein interactions, which is important for its role in cell signaling.

PDLIM3 is also involved in several cellular processes that are important for maintaining tissue structure and function. For example, it is involved in the regulation of cell adhesion, which is important for the development and maintenance of tissues such as tissues and organs. Additionally, PDLIM3 is involved in the regulation of cell proliferation, which is important for the growth and development of tissues.

PDLIM3 is also a potential drug target. Its unique structure and function make it an attractive target for drug development. Researchers have identified several potential drug candidates that target PDLIM3, including small molecules, peptides, and antibodies. These drugs have been shown to have a variety of biological effects, including inhibition of cell proliferation and modulation of cellular signaling pathways.

In addition to its potential as a drug target, PDLIM3 is also a valuable biomarker for several diseases. Its expression is often reduced in tissues of diseases, such as cancer, neurodegenerative diseases, and cardiovascular diseases. This suggests that PDLIM3 may be a useful biomarker for these diseases. Additionally, its unique structure and function make it a potential target for diagnostic tests, such as imaging agents and biochemical assays.

In conclusion, PDLIM3 is a unique and highly conserved protein that is involved in several cellular processes important for tissue structure and function. Its unique structure and function make it an attractive target for drug development, as well as a valuable biomarker for several diseases. Further research is needed to fully understand its role in cell signaling and its potential as a drug and biomarker.

Protein Name: PDZ And LIM Domain 3

Functions: May play a role in the organization of actin filament arrays within muscle cells

The "PDLIM3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PDLIM3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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