Regulation of Gene Expression and Stem Cell Proliferation By GTF3A

Target Name: GTF3A

NCBI ID: G2971

GTF3A

Regulation of Gene Expression and Stem Cell Proliferation By GTF3A

GTF3A, also known as Transcription factor IIIA, is a protein that plays a crucial role in gene expression and cell development. It is a transcription factor that is responsible for regulating gene expression by binding to specific DNA sequences. GTF3A is a key regulator of stem cell proliferation and differentiation, and it has been linked to a number of diseases, including cancer. As a result, GTF3A has become a focus of interest for researchers studying the causes and potential treatments for these diseases.

One of the key functions of GTF3A is its role in regulating the expression of genes that are involved in cell growth and differentiation. This is done by binding to specific DNA sequences and then using this binding to control the activity of the genes it binds to. This allows GTF3A to have a powerful impact on gene expression and cell development.

In addition to its role in cell development, GTF3A is also involved in the regulation of stem cell proliferation. stem cells are a type of cell that have the ability to develop into any type of cell in the body, and they have the potential to be used to treat a wide range of diseases. GTF3A plays a key role in regulating the proliferation of stem cells by controlling the activity of genes that are involved in cell growth and differentiation.

GTF3A has also been linked to a number of diseases, including cancer. Many studies have shown that GTF3A is often expressed in tissues that are affected by cancer, and that it plays a role in the regulation of cell growth and differentiation in these tissues. This suggests that GTF3A may be a useful target for cancer therapies.

Another potential use for GTF3A is as a biomarker. By measuring the level of GTF3A in tissues, researchers can get a sense of how well a treatment is working and how much it is affecting the expression of GTF3A. This could be a useful tool for researchers studying the effects of different treatments on cancer cells.

In conclusion, GTF3A is a protein that plays a crucial role in gene expression and cell development. It is a transcription factor that is responsible for regulating gene expression by binding to specific DNA sequences. GTF3A is also involved in the regulation of stem cell proliferation and has been linked to a number of diseases, including cancer. As a result, GTF3A has become a focus of interest for researchers studying the causes and potential treatments for these diseases. Further research is needed to fully understand the role of GTF3A in cell biology and to develop effective treatments for the diseases associated with it.

Protein Name: General Transcription Factor IIIA

Functions: Involved in ribosomal large subunit biogenesis. Binds the approximately 50 base pairs internal control region (ICR) of 5S ribosomal RNA genes. It is required for their RNA polymerase III-dependent transcription and may also maintain the transcription of other genes (PubMed:24120868). Also binds the transcribed 5S RNA's (By similarity)

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•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
•   disease relevance;
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•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
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