GTF3C3: A Protein Regulating Gene Expression and Cell Development

Target Name: GTF3C3

NCBI ID: G9330

GTF3C3

GTF3C3: A Protein Regulating Gene Expression and Cell Development

General transcription factor 3C (GTF3C3) is a protein that plays a crucial role in gene regulation and cell development. It is a member of the GTF3 family, which includes several similar proteins that regulate gene expression. GTF3C3 is a 21-kDa protein that is expressed in a variety of tissues and cells, including stem cells, tissues, and organs.

One of the key functions of GTF3C3 is to bind to specific DNA sequences and regulate the activity of transcription factors that are involved in gene expression. This protein is highly conserved, with a high degree of sequence identity between different isoforms. There are several different isoforms of GTF3C3, which are produced by alternative splicing of the gene.

One of the key applications of GTF3C3 is as a drug target. GTF3C3 has been shown to play a role in a variety of cellular processes, including cell growth, differentiation, and survival. It is also involved in several diseases, including cancer, neurodegenerative diseases , and developmental disorders. As a drug target, GTF3C3 may be used to treat a range of conditions that are caused by changes in gene expression.

One potential approach to targeting GTF3C3 as a drug is to use small molecules that can inhibit its activity. This can be done by binding to specific regions of the protein and preventing it from interacting with transcription factors. There are several different small molecules that have been shown to be effective at inhibiting GTF3C3 activity, including inhibitors of DNA binding and RNA binding.

Another potential approach to targeting GTF3C3 as a drug is to use antibodies that can selectively bind to the protein. This can be done by using antibodies that are specific for GTF3C3, but not for its downstream targets. This approach can be useful for identifying and targeting specific proteins that are involved in a variety of cellular processes.

In addition to its potential as a drug target, GTF3C3 is also a potential biomarker. This is because it is a protein that is expressed in a variety of tissues and cells, and its levels can be used to track changes in gene expression. This can be done by using techniques such as qRT-PCR, which is a reverse transcription polymerase-based amplification technique that can be used to measure the levels of GTF3C3 in a variety of samples.

GTF3C3 is also involved in several cellular processes that are important for normal development and function. For example, it is involved in the regulation of cell proliferation and differentiation, and it is involved in the formation of tissues and organs during development. In addition, GTF3C3 is involved in the regulation of cellular signaling pathways, including the TGF-β pathway. This pathway is involved in the regulation of cell growth, differentiation, and survival, and is a key factor in the development and maintenance of tissues and organs.

In conclusion, GTF3C3 is a protein that plays a crucial role in gene regulation and cell development. As a drug target, it may be used to treat a variety of conditions that are caused by changes in gene expression. In addition, GTF3C3 is also a potential biomarker that can be used to track changes in gene expression. Further research is needed to fully understand the role of GTF3C3 in cellular processes and its potential as a drug and biomarker.

Protein Name: General Transcription Factor IIIC Subunit 3

Functions: Involved in RNA polymerase III-mediated transcription. Integral, tightly associated component of the DNA-binding TFIIIC2 subcomplex that directly binds tRNA and virus-associated RNA promoters

The "GTF3C3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GTF3C3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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