GTF3C4: Key Component of T-Cell Antigen Presentation (G9329)

Target Name: GTF3C4

NCBI ID: G9329

GTF3C4

GTF3C4: Key Component of T-Cell Antigen Presentation

GTF3C4, also known as TFIIIC 90 kDa subunit, is a protein that is expressed in various tissues throughout the body. It is a key component of the T-cell antigen presentation pathway, where antigens are processed and loaded onto the major histocompatibility complex (MHC ) molecules on the surface of T-cells. GTF3C4 is a 90 kDa subunit of the T-cell antigen presentation pathway and is involved in the loading of the antigens onto the MHC class I molecules.

GTF3C4 is a protein that is expressed in various tissues throughout the body, including the spleen, Peyer's patches, and the skin. It is also expressed in the testes and thymus, which are responsible for the production of T-cells. GTF3C4 is a 90 kDa subunit of the T-cell antigen presentation pathway and is involved in the loading of antigens onto the MHC class I molecules.

The T-cell antigen presentation pathway is critical for the recognition of foreign antigens by T-cells. The pathway involves the phagocytosis of antigens by dendritic cells, which activates the T-cells and leads to the loading of the antigens onto the MHC class I molecules. GTF3C4 is a key component of this pathway, as it helps to load the antigens onto the MHC class I molecules.

GTF3C4 is a protein that is involved in the loading of antigens onto the MHC class I molecules. These molecules are responsible for presenting antigens to T-cells, and different MHC class I molecules have different antigen specificity. Antigens from intracellular antigens, such as viruses and tumor antigens, to T-cells. MHC class II molecules are responsible for presenting antigens from extracellular antigens, such as bacteria and viruses, to T-cells.

GTF3C4 is a critical protein for the recognition of intracellular antigens by T-cells. It is involved in the loading of these antigens onto the MHC class I molecules, which allows T-cells to recognize and respond to these antigens. GTF3C4 is also involved in the loading of extracellular antigens onto the MHC class II molecules, which allows T-cells to recognize and respond to these antigens.

In conclusion, GTF3C4 is a protein that is involved in the T-cell antigen presentation pathway. It is a key component of the loading of antigens onto the MHC class I molecules and is involved in the recognition of intracellular and extracellular antigens by T-cells . As a result, GTF3C4 may be a drug target or biomarker for various T-cell-related diseases, including cancer, autoimmune diseases, and infectious diseases. Further research is needed to fully understand the role of GTF3C4 in the T-cell antigen presentation. pathway and its potential as a drug target or biomarker.

Protein Name: General Transcription Factor IIIC Subunit 4

Functions: Essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA, tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin. Has histone acetyltransferase activity (HAT) with unique specificity for free and nucleosomal H3. May cooperate with GTF3C5 in facilitating the recruitment of TFIIIB and RNA polymerase through direct interactions with BRF1, POLR3C and POLR3F. May be localized close to the A box

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