Target Name: HDGF
NCBI ID: G3068
Review Report on HDGF Target / Biomarker Content of Review Report on HDGF Target / Biomarker
HDGF
Other Name(s): heparin binding growth factor | High mobility group protein 1-like 2 | hepatoma derived growth factor | HDGF variant 1 | HMG1L2 | Hepatoma-derived growth factor | Hepatoma-derived growth factor (isoform a) | Heparin binding growth factor, transcript variant 1 | HDGF_HUMAN | HMG-1L2 | epididymis secretory sperm binding protein | high mobility group protein 1-like 2

HDGF: A Drug Target / Disease Biomarker

HDGF, also known as heparin-derived growth factor, is a protein that is naturally occurring in the body. It is a key regulator of cell growth and differentiation, and is often used as a drug target or biomarker. In this article, we will discuss the science behind HDGF and its potential as a drug target.

HDGF was first identified in the 1970s by researchers who were studying the growth factors that were present in the body. They found that heparin, a common ingredient in some medications, was able to stimulate the growth of cells. This phenomenon was later confirmed by experiments conducted by Dr. Paul signal, who showed that heparin was able to stimulate the growth of cancer cells in a culture dish.

Since then, researchers have continued to study HDGF and its role in the body. They have found that HDGF is involved in many important processes in the body, including cell growth, migration, and invasion. It is also involved in the development and maintenance of tissues, such as blood vessels and bones.

One of the key functions of HDGF is its ability to stimulate cell growth. This is accomplished through the interaction between HDGF and its receptor, which is found on the surface of many different types of cells. When HDGF binds to its receptor, it can trigger a signaling cascade that tells the cell to start dividing and growing. This is what allows HDGF to promote the growth and development of tissues in the body.

Another important function of HDGF is its role in the immune system. It is involved in the development and maintenance of immune cells, including T cells and natural killer cells. These cells are important for protecting the body against viruses, bacteria, and other harmful substances that may enter the body.

In addition to its role in cell growth and development, HDGF is also involved in the regulation of pain. Studies have shown that HDGF is able to reduce the amount of pain that is felt by animals when they are subjected to certain types of pain. This may be because HDGF can inhibit the production of pain-causing chemicals in the body.

As a drug target, HDGF has the potential to be used to treat a wide range of conditions. For example, it is being studied as a potential treatment for cancer, due to its ability to stimulate cell growth and its potential to inhibit the production of cancer-promoting chemicals. It is also being studied as a potential treatment for other conditions, such as heart disease and neurodegenerative diseases.

In conclusion, HDGF is a protein that is naturally occurring in the body. It is involved in many important processes in the body, including cell growth, migration, and invasion. It is also involved in the development and maintenance of tissues and in the regulation of pain. As a drug target, HDGF has the potential to be used to treat a wide range of conditions. Further research is needed to fully understand its potential and to develop safe and effective treatments.

Protein Name: Heparin Binding Growth Factor

Functions: Acts as a transcriptional repressor (PubMed:17974029). Has mitogenic activity for fibroblasts (PubMed:11751870, PubMed:26845719). Heparin-binding protein (PubMed:15491618)

The "HDGF Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about HDGF comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

HDGFL1 | HDGFL2 | HDGFL3 | HDHD2 | HDHD3 | HDHD5 | HDHD5-AS1 | HDLBP | HDX | Heat Shock Protein 27 (Hsp27) | Heat shock protein 70 | Heat shock protein 90 | HEAT2 | HEATR1 | HEATR3 | HEATR4 | HEATR5A | HEATR5B | HEATR6 | HEATR6-DT | HEATR9 | HEBP1 | HEBP2 | HECA | HECTD1 | HECTD2 | HECTD2-AS1 | HECTD3 | HECTD4 | HECW1 | HECW2 | Hedgehog Protein | HEG1 | HEIH | HELB | HELLS | HELQ | HELT | HELZ | HELZ2 | Heme Oxygenase (HO) | HEMGN | HEMK1 | Hemoglobin A-2 (HbA-2) | Hemoglobulin A (HbA) | HENMT1 | HEPACAM | HEPACAM2 | HEPH | HEPHL1 | HEPN1 | HER (erbB) | HERC1 | HERC2 | HERC2P10 | HERC2P2 | HERC2P3 | HERC2P4 | HERC2P5 | HERC2P7 | HERC2P8 | HERC2P9 | HERC3 | HERC4 | HERC5 | HERC6 | HERPUD1 | HERPUD2 | HES1 | HES2 | HES3 | HES4 | HES5 | HES6 | HES7 | HESX1 | Heterogeneous nuclear ribonucleoprotein complex | HEXA | HEXA-AS1 | HEXB | HEXD | HEXIM1 | HEXIM2 | Hexokinase | HEY1 | HEY2 | HEY2-AS1 | HEYL | HFE | HFM1 | HGC6.3 | HGD | HGF | HGFAC | HGH1 | HGS | HGSNAT | HHAT | HHATL | HHEX