Target Name: HECTD4
NCBI ID: G283450
Review Report on HECTD4 Target / Biomarker Content of Review Report on HECTD4 Target / Biomarker
HECTD4
Other Name(s): FLJ10510 | MGC126531 | HEEL | C12ord51 | HECD4_HUMAN | HECT domain-containing protein 4 | probable E3 ubiquitin-protein ligase C12orf51 | Probable E3 ubiquitin-protein ligase HECTD4 | Probable E3 ubiquitin-protein ligase C12orf51 | C12orf51 | Transmembrane protein C12orf51 | FLJ34154 | Chromosome 12 open reading frame 51 | transmembrane protein C12orf51 | AF-1 specific protein phosphatase | KIAA0614 | FLJ30208 | HECT-type E3 ubiquitin transferase HECTD4 | FLJ30092 | POTAGE | HECT domain containing E3 ubiquitin protein ligase 4 | HECT domain E3 ubiquitin protein ligase 4 | DKFZp586O1022

HECTD4: Potential Drug Target Or Biomarker for Various Diseases

HECTD4, also known as FLJ10510, is a protein that is expressed in a variety of tissues and cells in the human body. It is a member of the HECT family of proteins, which are known for their role in regulating DNA damage and repair. HECTD4 has been shown to play a key role in the regulation of cell growth, apoptosis, and inflammation. As a result, it has potential as a drug target or biomarker for a variety of diseases.

One of the key functions of HECTD4 is its role in regulating cell growth. The HECTD4 protein functions as a negative regulator of the S/N ratio, which is the ratio of short to long double-stranded DNA in a cell. The S/N ratio is critical for the regulation of cell growth, as it determines the degree of DNA damage that can be repaired by the cell. HECTD4 helps to maintain a proper S/N ratio, which is essential for the growth and development of tissues and organs.

Another function of HECTD4 is its role in apoptosis. Apoptosis is a natural process that is involved in the regulation of cell life cycle. It is essential for the development and maintenance of tissues and organs, and it helps to remove damaged or dysfunctional cells. HECTD4 has been shown to play a key role in the regulation of apoptosis, as it is involved in the formation of the apoptotic machinery.

In addition to its role in cell growth and apoptosis, HECTD4 is also involved in the regulation of inflammation. It has been shown to play a key role in the regulation of immune cell function, as it is involved in the production of pro-inflammatory cytokines. HECTD4 helps to maintain a proper balance between pro-inflammatory and anti-inflammatory cytokines, which is essential for the regulation of a healthy immune response.

Due to its involvement in so many important cellular processes, HECTD4 has potential as a drug target or biomarker for a variety of diseases. For example, HECTD4 has been shown to be involved in the development of cancer, and may be a useful target for anti-cancer drugs. Additionally, HECTD4 has been associated with a variety of inflammatory diseases, and may be a useful biomarker for monitoring the effectiveness of anti-inflammatory treatments.

In conclusion, HECTD4 is a protein that plays a critical role in the regulation of cell growth, apoptosis, and inflammation. As a result, it has potential as a drug target or biomarker for a variety of diseases. Further research is needed to fully understand the role of HECTD4 in these processes and to develop effective treatments based on its properties.

Protein Name: HECT Domain E3 Ubiquitin Protein Ligase 4

Functions: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates

The "HECTD4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about HECTD4 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

HECW1 | HECW2 | Hedgehog Protein | HEG1 | HEIH | HELB | HELLS | HELQ | HELT | HELZ | HELZ2 | Heme Oxygenase (HO) | HEMGN | HEMK1 | Hemoglobin A-2 (HbA-2) | Hemoglobulin A (HbA) | HENMT1 | HEPACAM | HEPACAM2 | HEPH | HEPHL1 | HEPN1 | HER (erbB) | HERC1 | HERC2 | HERC2P10 | HERC2P2 | HERC2P3 | HERC2P4 | HERC2P5 | HERC2P7 | HERC2P8 | HERC2P9 | HERC3 | HERC4 | HERC5 | HERC6 | HERPUD1 | HERPUD2 | HES1 | HES2 | HES3 | HES4 | HES5 | HES6 | HES7 | HESX1 | Heterogeneous nuclear ribonucleoprotein complex | HEXA | HEXA-AS1 | HEXB | HEXD | HEXIM1 | HEXIM2 | Hexokinase | HEY1 | HEY2 | HEY2-AS1 | HEYL | HFE | HFM1 | HGC6.3 | HGD | HGF | HGFAC | HGH1 | HGS | HGSNAT | HHAT | HHATL | HHEX | HHIP | HHIP-AS1 | HHIPL1 | HHIPL2 | HHLA1 | HHLA2 | HHLA3 | HIBADH | HIBCH | HIC1 | HIC2 | HID1 | HID1-AS1 | HIF1A | HIF1A-AS1 | HIF1A-AS2 | HIF1A-AS3 | HIF1AN | HIF3A | HIGD1A | HIGD1AP1 | HIGD1AP10 | HIGD1B | HIGD1C | HIGD2A | HIGD2B | High affinity cAMP-specif | High Affinity Immunoglobulin Epsilon Fc Receptor | HIKESHI