Target Name: HDLBP
NCBI ID: G3069
Review Report on HDLBP Target / Biomarker Content of Review Report on HDLBP Target / Biomarker
HDLBP
Other Name(s): HBP | Vigilin (isoform a) | FLJ16432 | High density lipoprotein binding protein, transcript variant 1 | HDL-binding protein | high density lipoprotein binding protein | PRO2900 | OTTHUMP00000164572 | VGL | Vigilin | High density lipoprotein-binding protein | OTTHUMP00000200288 | HDLBP variant 1 | VIGLN_HUMAN

HDLBP: A Drug Target / Disease Biomarker

HDLBP, or high-density lipid protein, is a protein that is found in the bloodstream. It is made up of four chains and has a molecular weight of 112 kDa. It is a scaffold protein that helps to transport fat throughout the body. It is also a protein that has been linked to an increased risk of heart disease, and so it is of interest as a potential drug target or biomarker.

One of the things that makes HDLBP an attractive target for drugs is its location in the body. It is found in high concentrations in the blood, and so it is easy to collect samples from the bloodstream. This makes it a good candidate for use in studies that want to test the effects of drugs on HDLBP levels in the body.

Another reason why HDLBP is an interesting target for drugs is its role in the development and progression of heart disease. It has been shown to be involved in the regulation of lipid metabolism, which is the process by which the body produces and uses fat. HDLBP has been shown to help control the levels of low-density lipid cholesterol (LDL) in the blood, which is a risk factor for heart disease.

In addition to its role in heart disease, HDLBP is also of interest as a potential biomarker for the disease. This is because it has been shown to be a reliable indicator of heart health in people without known heart disease. Researchers have been able to use HDLBP as a marker to predict the risk of heart disease in people with normal test scores, and they have also found that HDLBP levels are often lower in people with heart disease.

Despite the potential benefits of HDLBP as a drug target or biomarker, there are also some potential drawbacks to consider. One of the main concerns is the potential side effects of any drugs that are used to target HDLBP. For example, some studies have suggested that HDLBP may cause muscle damage, which could be a potential side effect of any drugs that are used to lower HDLBP levels.

Another potential drawback of HDLBP is its location in the body. As mentioned earlier, HDLBP is found in high concentrations in the blood, which means that it is easy to collect samples from the bloodstream. This could make it difficult to study the effects of drugs on HDLBP levels in the body, as it may be difficult to determine whether the observed changes in HDLBP levels are due to the effects of the drug or to the natural changes that occur in the body.

Despite these potential drawbacks, research on HDLBP is still in its early stages. There are currently only a few studies that have been conducted to investigate the effects of drugs on HDLBP levels, and more research is needed to fully understand the potential of this protein as a drug target or biomarker.

In conclusion, HDLBP is a protein that is found in the bloodstream and has been linked to an increased risk of heart disease. It is also a protein that has been shown to be involved in the regulation of lipid metabolism and has been shown to be a reliable indicator of heart health in people without known heart disease. As a result, HDLBP is of interest as a potential drug target or biomarker, and further research is needed to fully understand its potential effects on the body.

Protein Name: High Density Lipoprotein Binding Protein

Functions: Appears to play a role in cell sterol metabolism. It may function to protect cells from over-accumulation of cholesterol

The "HDLBP Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about HDLBP comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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