Understanding HELZ2: Potential Drug Targets for DNA Replication and Cell Growth

Target Name: HELZ2

NCBI ID: G85441

HELZ2

Understanding HELZ2: Potential Drug Targets for DNA Replication and Cell Growth

Helicase with zinc finger domain 2 (HELZ2) is a protein that is expressed in various tissues throughout the body. It is a key player in the regulation of DNA replication and has been linked to a number of diseases, including cancer. In recent years, researchers have been interested in investigating the potential drug targets of HELZ2 and have identified several potential targets that could be targeted with small molecules.

One potential drug target for HELZ2 is the regulation of DNA replication. DNA replication is a critical process that is essential for the growth and development of all living organisms. HELZ2 has been shown to play a role in the regulation of DNA replication by ensuring that the proper number of copies of the genetic material are made. In addition, HELZ2 has been shown to interact with DNA-binding proteins, which could help to ensure that the DNA replication process is properly regulated.

Another potential drug target for HELZ2 is the regulation of cell growth. HELZ2 has been shown to play a role in the regulation of cell growth by ensuring that cells do not grow too quickly or too slowly. In addition, HELZ2 has been shown to interact with cell-cycle proteins, which could help to ensure that cells are able to navigate the cell cycle and divide properly.

In addition to its role in the regulation of DNA replication and cell growth, HELZ2 has also been shown to be involved in a number of other processes that are important for the survival and health of cells. For example, HELZ2 has been shown to play a role in the regulation of gene expression, which could help to ensure that cells are able to express the necessary proteins for their survival and function. In addition, HELZ2 has been shown to play a role in the regulation of cellular stress, which could help to ensure that cells are able to withstand environmental stressors and maintain their integrity.

Despite the potential drug targets for HELZ2, much more research is needed to fully understand its role in the regulation of DNA replication and cell growth. In addition, the use of small molecules as drug treatments for HELZ2 should be carefully evaluated to ensure that they are safe and effective.

In conclusion, Helicase with zinc finger domain 2 (HELZ2) is a protein that is expressed in various tissues throughout the body and is involved in a number of important processes that are essential for the survival and health of cells. The regulation of DNA replication and cell growth are two potential drug targets for HELZ2, and further research is needed to fully understand its role in these processes. The use of small molecules as drug treatments for HELZ2 should be carefully evaluated to ensure that they are safe and effective.

Protein Name: Helicase With Zinc Finger 2

Functions: Helicase that acts as a transcriptional coactivator for a number of nuclear receptors including PPARA, PPARG, THRA, THRB and RXRA

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•   general information;
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•   the target screening and validation;
•   expression level;
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