Target Name: POLR1H
NCBI ID: G30834
Review Report on POLR1H Target / Biomarker Content of Review Report on POLR1H Target / Biomarker
POLR1H
Other Name(s): A12.2 | ZR14 | POLR1H variant a | POLR1H variant b | ZNRD1 | RNA polymerase I subunit H, transcript variant a | hZR14 | RNA polymerase I subunit H | TEX6 | tctex-6 | RNA polymerase I subunit H, transcript variant b | Zinc ribbon domain-containing protein 1 | HTEX6 | Tctex-6 | RPA12 | TCTEX6 | RPA12_HUMAN | transcription-associated zinc ribbon protein | DNA-directed RNA polymerase I subunit RPA12 | Rpa12 | TCTEX-6 | RNA polymerase I small specific subunit Rpa12 | Transcription-associated zinc ribbon protein | DNA-directed RNA polymerase I subunit H | zinc ribbon domain containing 1 | HTEX-6

POLR1H: A Potential Drug Target and Biomarker

PolR1H is a gene that has been identified as a potential drug target in the field of genetics. It is a non-coding RNA molecule that plays a role in the regulation of gene expression. Studies have shown that alterations in the levels of PolR1H have been associated with a number of diseases, including cancer, neurodegenerative diseases, and developmental disorders.

One of the key features of PolR1H is its ability to interact with other proteins, known as RNA factors. These proteins can either activate or inhibit the activity of PolR1H depending on the specific context. One of the most well-studied RNA factors that interacts with PolR1H is called miRNA-181c.

MiRNA-181c is a non-coding RNA molecule that is typically expressed at low levels in the cell. It has been shown to play a role in the regulation of gene expression by binding to specific target genes and activating or inhibiting their activity. Studies have shown that miRNA-181c can interact with PolR1H and that this interaction may play a role in the regulation of gene expression.

Another RNA factor that has been shown to interact with PolR1H is called HIF1伪. HIF1伪 is a transcription factor that is involved in the regulation of gene expression in response to changes in oxygen levels. Studies have shown that HIF1伪 can interact with PolR1H and that this interaction may play a role in the regulation of gene expression.

In addition to these RNA factors, PolR1H has also been shown to interact with a number of protein molecules that are involved in the regulation of gene expression. These include factors such as RNA-protein interactions, histone modifications, and microRNA-protein interactions.

Given the complexity of the interactions between PolR1H and other molecules, it is important to consider the potential implications of these interactions for drug development. Identification of potential drug targets and biomarkers based on the interactions between PolR1H and other molecules could lead to new treatments for a variety of diseases.

Protein Name: RNA Polymerase I Subunit H

Functions: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors

The "POLR1H Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about POLR1H comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

POLR1HASP | POLR2A | POLR2B | POLR2C | POLR2D | POLR2E | POLR2F | POLR2G | POLR2H | POLR2I | POLR2J | POLR2J2 | POLR2J3 | POLR2J4 | POLR2K | POLR2L | POLR2LP1 | POLR2M | POLR3A | POLR3B | POLR3C | POLR3D | POLR3E | POLR3F | POLR3G | POLR3GL | POLR3H | POLR3K | POLRMT | POLRMTP1 | Poly [ADP-ribose] polymerase | Polycomb Repressive Complex 1 (PRC1) | Polycomb Repressive Complex 2 | POM121 | POM121B | POM121C | POM121L12 | POM121L15P | POM121L1P | POM121L2 | POM121L4P | POM121L7P | POM121L8P | POM121L9P | POMC | POMGNT1 | POMGNT2 | POMK | POMP | POMT1 | POMT2 | POMZP3 | PON1 | PON2 | PON3 | POP1 | POP4 | POP5 | POP7 | POPDC2 | POPDC3 | POR | PORCN | POSTN | POT1 | POT1-AS1 | Potassium Channels | POTEA | POTEB | POTEB2 | POTEB3 | POTEC | POTED | POTEE | POTEF | POTEG | POTEH | POTEI | POTEJ | POTEKP | POTEM | POU-Domain transcription factors | POU1F1 | POU2AF1 | POU2AF2 | POU2AF3 | POU2F1 | POU2F2 | POU2F3 | POU3F1 | POU3F2 | POU3F3 | POU3F4 | POU4F1 | POU4F2 | POU4F3 | POU5F1 | POU5F1B | POU5F1P3 | POU5F1P4