Novel Gene NOP14-AS1: Potential Drug Target and Biomarker (G317648)

Target Name: NOP14-AS1

NCBI ID: G317648

NOP14-AS1

Other Name(s): C4orf10 | RES4-24 | RP11-520M5.5 | NOP14 antisense RNA 1

Novel Gene NOP14-AS1: Potential Drug Target and Biomarker

NOP14-AS1 (C4orf10), a novel gene located on chromosome 14, has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and psychiatric disorders. The gene encodes a protein known as NOP14, which has been shown to play a crucial role in a variety of cellular processes, including cell adhesion, migration, and survival.

The discovery of NOP14-AS1 was made using a combination of genomic screening, transcriptomic analysis, and biochemical assays. The gene was identified using a publicly available database that was designed to identify gene duplications in high-throughput sequencing (HTS) data. The gene was then confirmed by RT-PCR and gene expression analysis.

NOP14 is a member of the N-cadherin subfamily of transmembrane proteins, which are known for their role in cell-cell adhesion and migration. The protein is involved in the regulation of cell adhesion, as well as the formation of tight junctions and the maintenance of cell-cell barriers. It has also been shown to play a role in the regulation of cell survival and the response to environmental stress.

In neurodegenerative diseases, NOP14 is thought to be involved in the development and progression of neurodegeneration. The protein has been shown to be expressed in the brains of individuals with neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. It is also suggested to be a potential therapeutic target for these diseases.

In addition to its potential role in neurodegenerative diseases, NOP14 is also being investigated as a potential drug target for other conditions, including cancer. The NOP14 gene has been shown to be highly expressed in a variety of cancer types, including breast, lung, and ovarian cancer. Studies have also shown that inhibition of NOP14 has the potential to enhance the effectiveness of some cancer treatments.

The potential applications of NOP14-AS1 as a drug target are vast. The protein has been shown to have a variety of potential therapeutic effects, including the inhibition of cell adhesion, the regulation of cell survival, and the modulation of cellular signaling pathways. It is possible that NOP14 could be used to treat a variety of neurodegenerative diseases, including Alzheimer's and Parkinson's disease, as well as certain types of cancer.

In conclusion, NOP14-AS1 is a promising gene that has the potential to be a drug target and biomarker for a variety of diseases. Further research is needed to fully understand the role of NOP14 in these conditions, as well as to develop safe and effective therapies that target this protein.

Protein Name: NOP14 Antisense RNA 1

The "NOP14-AS1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NOP14-AS1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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