NPEPPS: A Potential Drug Target for Anxiety and Depression (G9520)

Target Name: NPEPPS

NCBI ID: G9520

NPEPPS

NPEPPS: A Potential Drug Target for Anxiety and Depression

NPEPPS, or N-acetyl-phenylalanine synthase, is a enzyme that plays a crucial role in the production of a neurotransmitter called norepinephrine. Norepinephrine is a key neurotransmitter that is involved in a variety of physiological processes in the brain, including mood regulation, arousal, and response to stress.

While norepinephrine is an essential neurotransmitter, it is often deficient in conditions such as anxiety and depression. This is where NPEPPS comes in. By studying the function of NPEPPS, researchers have identified potential new drug targets for treating these conditions.

One of the ways that NPEPPS is being studied is as a potential drug target for anxiety and depression. NPEPPS has been shown to play a role in the production of norepinephrine, which is a neurotransmitter that is involved in the formation of new brain cells and the regulation of neurotransmitter release. By interfering with NPEPPS, researchers have been able to reduce the production of norepinephrine and improve mood in animals models of anxiety and depression.

Another way that NPEPPS is being studied is as a potential biomarker for depression. NPEPPS has been shown to be involved in the production of other neurotransmitters, including serotonin and dopamine. By analyzing the levels of these neurotransmitters in individuals with depression, researchers have been able to identify NPEPPS as a potential biomarker for depression. This biomarker has the potential to be used in the development of new diagnostic tests for depression and may also be a target for new treatments.

In addition to its potential as a drug target and biomarker, NPEPPS is also being studied for its potential role in the treatment of other conditions. For example, NPEPPS has been shown to play a role in the production of norepinephrine, which is involved in the regulation of heart rate. This suggests that NPEPPS may have potential applications in the treatment of conditions such as hypertension and heart failure.

Overall, NPEPPS is an important enzyme that is involved in a variety of physiological processes in the brain. Its role in the production of norepinephrine makes it a potential drug target and biomarker for a variety of conditions, including anxiety and depression. As research continues to advance, NPEPPS is likely to play an increasingly important role in the development of new treatments for these conditions.

Protein Name: Aminopeptidase Puromycin Sensitive

Functions: Aminopeptidase with broad substrate specificity for several peptides. Involved in proteolytic events essential for cell growth and viability. May act as regulator of neuropeptide activity. Plays a role in the antigen-processing pathway for MHC class I molecules. Involved in the N-terminal trimming of cytotoxic T-cell epitope precursors. Digests the poly-Q peptides found in many cellular proteins. Digests tau from normal brain more efficiently than tau from Alzheimer disease brain

The "NPEPPS Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NPEPPS comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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