Target Name: NOS1
NCBI ID: G4842
Review Report on NOS1 Target / Biomarker Content of Review Report on NOS1 Target / Biomarker
NOS1
Other Name(s): nitric oxide synthase 1 (neuronal) | NC-NOS | NNOS | NOS type I | NOS | N-NOS | neuronal NOS | IHPS1 | Nitric oxide synthase, brain (isoform 1) | NOS1_HUMAN | Neuronal nitric oxide synthase (nNOS) | constitutive NOS | BNOS | peptidyl-cysteine S-nitrosylase NOS1 | Nitric oxide synthase 1, transcript variant 1 | Neuronal NOS | Nitric oxide synthase, brain | NOS1 variant 1 | Peptidyl-cysteine S-nitrosylase NOS1 | bNOS | nitric oxide synthase 1 | Constitutive NOS | nNOS

NOS1: Nitric Oxide Synthase 1

NOS1 (Nitric Oxide Synthase 1) is a gene that encodes a protein involved in the production of nitric oxide (NO) in the body. Nitric oxide is a signaling molecule that plays a critical role in various physiological processes, including cardiovascular health, immune function , and neurotransmission. Unfortunately, NOS1 has also been associated with a number of diseases, including cardiovascular disease, cancer, and neurodegenerative disorders.

One of the main functions of NOS1 is to produce nitric oxide, which is a molecule that plays a central role in the regulation of blood flow and blood pressure. Nitric oxide is produced by the endothelium, which is the lining of the blood vessels, and it helps to relax the smooth muscle in the blood vessels, allowing blood to flow more easily.

NOS1 has also been shown to play a key role in the regulation of immune function. In particular, NOS1 has been shown to be involved in the production of NO by the immune cells known as neutrophils. Neutrophils are a type of white blood cell that play a critical role in fighting off infections and inflammation in the body. When neutrophils are exposed to an infection or inflammation, they produce NO to help them kill off the offending agent.

In addition to its role in immune function, NOS1 has also been shown to be involved in the regulation of neurotransmission. Neurons are the structural and functional units of the nervous system, and they use a variety of signaling molecules, including NO, to communicate with one another. NOS1 has been shown to play a key role in the production of NO by neurons, which allows it to transmit signals along the neural fibers.

Despite its many functions, NOS1 has also been linked to a number of diseases. One of the most well-known is cardiovascular disease, which is a leading cause of death in adults worldwide. Researchers have found that NOS1 is often expressed at higher levels in the hearts of individuals with cardiovascular disease, and that it is associated with decreased nitric oxide production. This may contribute to the development and progression of cardiovascular disease.

In addition to cardiovascular disease, NOS1 has also been associated with a number of other diseases, including cancer and neurodegenerative disorders. For example, studies have found that NOS1 is often expressed at higher levels in the brains of individuals with Alzheimer's disease, a type of neurodegenerative disorder. This may suggest that NOS1 plays a role in the development and progression of neurodegenerative diseases.

Despite its many functions and associations with disease, NOS1 is still an enigmatic protein. There is ongoing research into the precise role of NOS1 in the regulation of various physiological processes, including immune function and neurotransmission. Future research will continue to explore the role of NOS1 in biology. function in them, and look for their potential use as drug targets or biomarkers.

Protein Name: Nitric Oxide Synthase 1

Functions: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR

The "NOS1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NOS1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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