Understanding NPM1P48: A Potential Drug Target and Biomarker (G442006)
Understanding NPM1P48: A Potential Drug Target and Biomarker
NPM1P48, also known as nucleophosmin 1 (nucleolar phosphoprotein B23) or numatrin, is a protein that plays a critical role in the regulation of DNA replication and cell growth. It is a key component of the nucleosome, which is the basic unit of DNA replication, and its levels have been linked to various cellular processes, including cell cycle progression, apoptosis, and aging.
In recent years, researchers have become increasingly interested in the potential drug targets of NPM1P48. This is because the protein has been shown to play a role in a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.
One of the key reasons for the interest in NPM1P48 as a drug target is its role in the development and progression of cancer. NPM1P48 has been shown to be overexpressed in a variety of cancer types, including breast, ovarian, and prostate cancer. Additionally, studies have shown that inhibiting NPM1P48 can lead to the growth inhibition and apoptosis of cancer cells.
Another potential drug target for NPM1P48 is its role in neurodegenerative diseases. NPM1P48 has been shown to be overexpressed in a variety of neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, and Huntington's disease. Additionally, studies have shown that inhibiting NPM1P48 can lead to the regression of neurodegenerative disease-associated symptoms in animal models.
In addition to its potential as a drug target, NPM1P48 has also been shown to be a potential biomarker for various diseases. For example, studies have shown that decreased NPM1P48 levels are associated with an increased risk of neurodegenerative disease in aging individuals. Additionally, increased NPM1P48 levels have been shown to be associated with the development of certain diseases, such as cancer.
Overall, the potential drug targets and biomarkers for NPM1P48 are significant and continue to be an area of ongoing research. As more studies are conducted, it is likely that we will gain a better understanding of the role of NPM1P48 in disease and its potential as a drug.
Protein Name: Nucleophosmin 1 Pseudogene 48
The "NPM1P48 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NPM1P48 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
NPM2 | NPM3 | NPNT | NPPA | NPPA-AS1 | NPPB | NPPC | NPR1 | NPR2 | NPR3 | NPRL2 | NPRL3 | NPS | NPSR1 | NPSR1-AS1 | NPTN | NPTN-IT1 | NPTX1 | NPTX2 | NPTXR | NPVF | NPW | NPY | NPY1R | NPY2R | NPY4R | NPY4R2 | NPY5R | NPY6R | NQO1 | NQO2 | NR0B1 | NR0B2 | NR1D1 | NR1D2 | NR1H2 | NR1H3 | NR1H4 | NR1I2 | NR1I3 | NR2C1 | NR2C2 | NR2C2AP | NR2E1 | NR2E3 | NR2F1 | NR2F1-AS1 | NR2F2 | NR2F2-AS1 | NR2F6 | NR3C1 | NR3C2 | NR4A1 | NR4A2 | NR4A3 | NR5A1 | NR5A2 | NR6A1 | NRAD1 | NRADDP | NRAP | NRARP | NRAS | NRAV | NRBF2 | NRBF2P4 | NRBP1 | NRBP2 | NRCAM | NRDC | NRDE2 | NREP | NRF1 | NRG1 | NRG2 | NRG3 | NRG4 | NRGN | NRIP1 | NRIP2 | NRIP3 | NRIP3-DT | NRIR | NRK | NRL | NRM | NRN1 | NRN1L | NRON | NRP1 | NRP2 | NRROS | NRSN1 | NRSN2 | NRSN2-AS1 | NRTN | NRXN1 | NRXN2 | NRXN2-AS1 | NRXN3
