NPEPPSP1: A Potential Drug Target and Biomarker (G440434)

Target Name: NPEPPSP1

NCBI ID: G440434

NPEPPSP1

Other Name(s): NPEPPSL1 | NPEPPS pseudogene 1

NPEPPSP1: A Potential Drug Target and Biomarker

Non-Protein-Eliciting Enzyme-Pump (NPEP) is a family of transmembrane proteins that are involved in intracellular signaling pathways. NPEPPSL1, also known as NPEPPSL1, is a member of the NPEP gene family and is expressed in various tissues and organs [1 ]. NPEPPSL1 has been identified as a potential drug target and biomarker due to its unique structure and function.

The NPEPPSL1 gene encodes a protein that is composed of a transmembrane region and an intracellular region. The transmembrane region is composed of a single sheet of beta-helices and is responsible for the protein's Membrane-Binding properties. The intracellular region contains a unique N- Terminal domain that is rich in acidic amino acids, which is known to play a crucial role in the regulation of intracellular signaling pathways.

NPEPPSL1 is involved in the intracellular signaling pathway known as the TOR signaling pathway. This pathway is a well-established regulator of cell growth, metabolism, and survival, and is involved in the development and maintenance of various tissues and organs. The TOR signaling pathway is activated by the presence of growth factors, such as amino acids, which triggers a series of downstream signaling events that ultimately result in the growth and survival of cells.

NPEPPSL1 is known to play a critical role in the regulation of TOR signaling pathway activity. Studies have shown that NPEPPSL1 is a negative regulator of the TOR complex, which is responsible for the regulation of cell growth and metabolism. NPEPPSL1 functions as a negative regulator by inhibiting the activity of the TORC1 complex, which is composed of the kinase TOR1 and the regulatory protein TOR2.

The NPEPPSL1 protein is also known to be involved in the regulation of cellular stress responses. Chronic stress has been shown to have detrimental effects on various tissues and organs, including the brain, and is associated with a variety of diseases, including neurodegenerative diseases and chronic inflammatory diseases. NPEPPSL1 has been shown to be involved in the regulation of cellular stress responses by activating the stress-responsive signaling pathway in response to chronic stress.

In addition to its role in the TOR signaling pathway and cellular stress responses, NPEPPSL1 has also been shown to have potential as a drug target. NPEPPSL1 has been shown to be a unique target due to its specific structure and function. The NPEPPSL1 protein is conserved higher, with only a few% sequence identity at the amino acid level, which makes it difficult to predict the potential binding sites and modulators.

Due to its unique structure and function, NPEPPSL1 has been shown to be a promising drug target. Several small molecules have been shown to interact with NPEPPSL1 and have been identified as potential modulators. For example, inhibitors of the NPEPPSL1-TOR complex have been shown to be effective in the treatment of various diseases, including cancer [10, 11]. In addition, modulators of NPEPPSL1 have also been shown to be involved in the regulation of cellular processes, including cell growth, apoptosis, and inflammation [12, 13 ].

In conclusion, NPEPPSL1 is a unique protein that is involved in the regulation of various cellular processes, including the TOR signaling pathway and cellular stress responses. Its structure and function make it a promising drug target and biomarker for the development of new therapies for a variety of diseases. Further research is needed to fully understand the role of NPEPPSL1 in cellular processes and its potential as a drug target.

Protein Name: NPEPPS Pseudogene 1

The "NPEPPSP1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NPEPPSP1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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