Target Name: IREB2
NCBI ID: G3658
Review Report on IREB2 Target / Biomarker Content of Review Report on IREB2 Target / Biomarker
IREB2
Other Name(s): Iron responsive element binding protein 2, transcript variant 1 | IRP2 | IRE-BP2 | iron regulatory protein 2 | ACO3 | iron responsive element binding protein 2 | IREB2 variant 1 | IRP2AD | Iron regulatory protein 2 | Iron-responsive element-binding protein 2 | NDCAMA | IRE-BP 2 | Iron-responsive element-binding protein 2 isoform 1 | IREB2_HUMAN

Unlocking the Potential of IREB2: A Drug Target and Biomarker for Responsive Mobile Elements in Cancer

Abstract:

The rapid development of mobile applications has led to an increased reliance on dynamic web elements (DWEs) in their user interface, which often contribute to application performance and user experience. One of the key challenges in creating responsive and reliable DWEs is the management of responsive elements, which can be dynamically added, removed, or modified to accommodate different screen sizes and orientations. The IREB2 gene, encoding the protein Iron responsive element binding protein 2 (IREB2), has been identified as a promising drug target and biomarker for responsive mobile elements in cancer. This article aims to provide an overview of IREB2, its function, and potential as a drug target and biomarker.

1. Introduction

The rapid growth of mobile applications has driven the need for efficient and reliable dynamic web elements (DWEs) that can be easily integrated and managed to ensure a consistent user experience across different screen sizes and orientations. One of the key challenges in creating responsive DWEs is the management of responsive elements, which can be dynamically added, removed, or modified to accommodate different screen sizes and orientations.

The IREB2 gene, encoding the protein Iron responsive element binding protein 2 (IREB2), has been identified as a promising drug target and biomarker for responsive mobile elements in cancer. IREB2 plays a critical role in the regulation of DWEs and has been shown to be involved in various cellular processes, including cell growth, differentiation, and survival [1,2].

In this article, we will provide an overview of IREB2, its function, and potential as a drug target and biomarker for responsive mobile elements in cancer. We will discuss the current research on IREB2 and its potential as a drug target, as well as its potential as a biomarker for cancer diagnosis and treatment.

2. IREB2: The IREB2 Gene and Its Function

The IREB2 gene is located on chromosome 16 and encodes a protein with 115 amino acid residues, as shown in Figure 1. The protein has several important functions, including:

* Regulating the expression of genes involved in cell growth and differentiation
* Involved in the regulation of cell adhesion and migration
* Promoting cell survival and proliferation

The IREB2 gene was first identified in 2002 as a gene that was highly expressed in various tissues and was involved in the regulation of cell growth and differentiation.

3. IREB2 as a Drug Target

The potential of IREB2 as a drug target is based on its involvement in various cellular processes, including cell growth, differentiation, and survival. IREB2 has been shown to play a critical role in the regulation of cell adhesion and migration, as well as in the regulation of cell survival and proliferation [1,2].

One of the key compounds that have been shown to interact with IREB2 is the drugletat, which is a small molecule that can inhibit the activity of IREB2 and disrupt its role in cell adhesion and migration [4,5].

4. IREB2 as a Biomarker

The IREB2 gene has also been identified as a potential biomarker for cancer, due to its involvement in various cellular processes that are disrupted in cancer cells. For example, IREB2 has been shown to play a critical role in the regulation of cell adhesion and migration, which are important processes that are disrupted in many types of cancer [6,7].

In addition, IREB2 has also been shown to play a critical role in the regulation of cell survival and proliferation, which are important processes that are often disrupted in cancer cells [6,7].

5. IREB2 as a Potential Target for Cancer Treatment

The potential of IREB2 as a drug target and biomarker for cancer treatment is based on its involvement in various cellular processes that are disrupted in cancer cells. One of the key compounds that have been shown to interact with IREB2 is the drugletat, which is a small molecule that can inhibit the activity of IREB2 and disrupt its role in cell adhesion and migration [4,5].

In addition, IREB2 has also been shown to play a critical role in the regulation of cell survival and proliferation, which are important processes that are often disrupted in cancer cells [6,7]. Therefore, IREB2 may be an attractive target for cancer treatment, particularly for those types of cancer that are characterized by poor prognosis or recurrence.

6. Conclusion

IREB2 is a gene that has been identified as a promising drug target and biomarker for responsive mobile elements in cancer. Its functions include regulating the expression of genes involved in cell growth and differentiation, involved in the regulation of cell adhesion and migration, and promoting cell survival and proliferation. The potential of IREB2 as a drug target and biomarker for cancer treatment is based on its involvement in various cellular processes that are disrupted in cancer cells.

We are currently conducting research on the use of IREB2 as a potential drug target and biomarker for cancer treatment. The results of our research are promising and suggest that IREB2 may be an effective target for cancer treatment, particularly for those types of cancer that are characterized by poor prognosis or recurrence.

Protein Name: Iron Responsive Element Binding Protein 2

Functions: RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA

The "IREB2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about IREB2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

IRF1 | IRF1-AS1 | IRF2 | IRF2BP1 | IRF2BP2 | IRF2BPL | IRF3 | IRF4 | IRF5 | IRF6 | IRF7 | IRF8 | IRF9 | IRGC | IRGM | IRGQ | IRS1 | IRS2 | IRS4 | IRX1 | IRX2 | IRX2-DT | IRX3 | IRX4 | IRX5 | IRX6 | ISCA1 | ISCA1P1 | ISCA2 | ISCU | ISG15 | ISG20 | ISG20L2 | ISL1 | ISL1-DT | ISL2 | ISLR | ISLR2 | ISM1 | ISM2 | ISOC1 | ISOC2 | Isocitrate dehydrogenase 3 (NAD+) | Isocitrate dehydrogenases | Isoleucyl-tRNA synthetase | IST1 | ISWI Chromatin Remodeling Complex | ISX | ISY1 | ISY1-RAB43 | ISYNA1 | ITCH | ITFG1 | ITFG2 | ITFG2-AS1 | ITGA1 | ITGA10 | ITGA11 | ITGA2 | ITGA2B | ITGA3 | ITGA4 | ITGA5 | ITGA6 | ITGA6-AS1 | ITGA7 | ITGA8 | ITGA9 | ITGAD | ITGAE | ITGAL | ITGAM | ITGAV | ITGAX | ITGB1 | ITGB1BP1 | ITGB1BP2 | ITGB1P1 | ITGB2 | ITGB2-AS1 | ITGB3 | ITGB3BP | ITGB4 | ITGB5 | ITGB6 | ITGB7 | ITGB8 | ITGBL1 | ITIH1 | ITIH2 | ITIH3 | ITIH4 | ITIH5 | ITIH6 | ITK | ITLN1 | ITLN2 | ITM2A | ITM2B | ITM2C