Understanding ISG20L2: A Potential Drug Target and Biomarker (G81875)

Target Name: ISG20L2

NCBI ID: G81875

ISG20L2

Understanding ISG20L2: A Potential Drug Target and Biomarker

Interferon-stimulated 20 kDa exonuclease-like 2 (ISG20L2) is a non-coding RNA molecule that has been identified as a potential drug target and biomarker for various diseases, including cancer. ISG20L2 is a member of the ISG2 family, which includes ISG2, ISG3, and ISG4, which are involved in the regulation of DNA double-strand break repair and other cellular processes. ISG20L2 is unique among these ISG genes because of its high stability and its ability to induce DNA double-strand breaks in a cell-type-specific manner.

The ISG2 family plays a crucial role in the regulation of DNA repair and genome stability. ISG20L2 is involved in the repair of double-strand breaks in the terminal exons of RNA genes, which are typically targeted for exonuclease activity. ISG20L2 functions by promoting the formation of a double-strand break at specific sites in the terminal exons of RNA genes, which are then repaired by homologous end joining or other repair pathways.

ISG20L2 has been shown to play a role in the regulation of various cellular processes, including cell growth, apoptosis, and DNA replication. For example, ISG20L2 has been shown to promote the growth of cancer cells and to contribute to their survival. It has also been shown to play a role in the regulation of apoptosis, with ISG20L2 being involved in the inhibition of programmed cell death (apoptosis).

In addition to its role in cellular processes, ISG20L2 has also been shown to be involved in the regulation of gene expression. For example, ISG20L2 has been shown to repress the expression of genes involved in cell adhesion, cell migration, and other processes that are important for cancer progression.

ISG20L2 has also been shown to be involved in the regulation of inflammation. For example, ISG20L2 has been shown to contribute to the regulation of inflammation-related genes and to play a role in the development of cancer.

Despite its potential as a drug target and biomarker, ISG20L2 is still poorly understood. Very little is known about the specific functions of ISG20L2 and its role in various cellular processes. There is also a lack of information about the underlying molecular mechanisms that regulate ISG20L2.

In conclusion, ISG20L2 is a non-coding RNA molecule that has been identified as a potential drug target and biomarker for various diseases. Its unique ability to induce DNA double-strand breaks in a cell-type-specific manner and its involvement in the regulation of various cellular processes make it an attractive target for further research. Further studies are needed to fully understand the functions of ISG20L2 and its potential as a drug.

Protein Name: Interferon Stimulated Exonuclease Gene 20 Like 2

Functions: 3'-> 5'-exoribonuclease involved in ribosome biogenesis in the processing of the 12S pre-rRNA. Displays a strong specificity for a 3'-end containing a free hydroxyl group

The "ISG20L2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ISG20L2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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