JPH1: A Potential Drug Target for Cancer and Neurodegenerative Diseases

Target Name: JPH1

NCBI ID: G56704

JPH1

JPH1: A Potential Drug Target for Cancer and Neurodegenerative Diseases

JPH1, also known as JPH1 variant 1, is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the tyrosine kinase family and is involved in the regulation of cell proliferation, differentiation, and survival.

JPH1 has been identified as a potential drug target and has been shown to play a role in several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its unique structure and function have made it an attractive target for researchers to study and develop new treatments.

One of the key challenges in studying JPH1 is its complex structure. JPH1 is a 21-kDa protein that consists of a N-terminus, a catalytic center, and a C-terminus. The N-terminus is involved in the protein's stability and functions as a receptor, while the C-terminus is involved in the protein's interactions with other proteins.

JPH1's catalytic center is a unique feature that has not been seen in other tyrosine kinase family proteins. It consists of a nucleotide-binding oligomerization (NBO) domain and a carboxy-terminal domain that are both involved in the regulation of protein function. The NBO domain is responsible for the protein's stability and functions as a nucleotide-binding protein, while the carboxy-terminal domain is involved in the regulation of the NBO domain's activity.

JPH1's role in cell proliferation and differentiation is also of interest. It has been shown to play a role in the regulation of cell growth, cell survival, and cell differentiation. For example, JPH1 has been shown to be involved in the regulation of neuronal plasticity , which is the ability of neurons to change and adapt in response to different stimuli.

JPH1's role in neurodegenerative diseases is also of interest. neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease, are characterized by the progressive loss of brain cells and the development of neurofibrillary tangles and neuroplasm. JPH1 has been shown to be involved in the regulation of neurodegenerative diseases, and its potential as a drug target makes it an attractive target for researchers to study.

In addition to its role in neurodegenerative diseases, JPH1 is also of interest in the regulation of cancer cell growth and survival. cancer is a leading cause of death worldwide, and its development and progression are tied closely to the regulation of cell growth and survival. JPH1 has been shown to play a role in the regulation of cancer cell growth and survival, which makes it an attractive target for cancer therapies.

JPH1's potential as a drug target also makes it an attractive target for researchers to study the effects of new drugs and to develop new treatments for a variety of diseases. Its unique structure and function have made it an attractive target for researchers to study, and its potential as a drug target has made it an important area of 鈥嬧?媟esearch in the field of molecular biology.

In conclusion, JPH1 is a protein that has been identified as a potential drug target and has been shown to play a role in several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its unique structure and function have made it an attractive target for researchers to study and develop new treatments. Further research is needed to fully understand its role in disease and to develop effective treatments.

Protein Name: Junctophilin 1

Functions: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH1 contributes to the construction of the skeletal muscle triad by linking the t-tubule (transverse-tubule) and SR (sarcoplasmic reticulum) membranes

The "JPH1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about JPH1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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