Target Name: TMPRSS11F
NCBI ID: G389208
Review Report on TMPRSS11F Target / Biomarker Content of Review Report on TMPRSS11F Target / Biomarker
TMPRSS11F
Other Name(s): airway trypsin-like protease 4 | Transmembrane protease serine 11F | transmembrane protease, serine 11F | Airway trypsin-like protease 4 | HATL4 | Transmembrane serine protease 11F | TM11F_HUMAN | transmembrane serine protease 11F

TMPRSS11F: A Potential Drug Target and Biomarker for Airway Trypsin-Like Protease 4

Airway trypsin-like protease 4 (TMPRSS11F) is a protein that is expressed in various cell types in the body, including epithelial and smooth muscle cells. TMPRSS11F is a member of the trypsin-like family of enzymes, which are involved in the processing of extracellular matrix (ECM) components, such as ECM proteins. This protein has been shown to play a role in various physiological processes, including cell signaling, tissue repair, and inflammation.

Recent studies have suggested that TMPRSS11F may have potential as a drug target or biomarker. In this article, we will explore the biology and potential drug targets of TMPRSS11F.

The Biology of TMPRSS11F

TMPRSS11F is a 21-kDa protein that is expressed in various cell types, including epithelial and smooth muscle cells. It is a member of the trypsin-like family of enzymes, which are involved in the processing of ECM components. TMPRSS11F is composed of a 152 amino acid protein that contains a single trypsin-like catalytic active site, as well as several non-catalytic regions.

TMPRSS11F has been shown to play a role in various physiological processes, including cell signaling, tissue repair, and inflammation. For example, TMPRSS11F has been shown to be involved in cell migration, invasion, and angiogenesis. It has also been shown to play a role in the regulation of cell apoptosis, a process that is involved in cell death.

In addition to its role in cell biology, TMPRSS11F has also been shown to have potential as a drug target. TMPRSS11F has been shown to interact with various drug molecules, including small molecules, peptides, and proteins. These interactions may be involved in the regulation of TMPRSS11F activity and could be potential drug targets.

Potential Drug Targets

Several studies have suggested that TMPRSS11F may have potential as a drug target. One potential drug target for TMPRSS11F is the inhibition of its trypsin-like activity. This could be achieved through inhibitors of TMPRSS11F trypsin-like activity, such as those that bind to the active site of the enzyme.

Another potential drug target for TMPRSS11F is its role in cell apoptosis. TMPRSS11F has been shown to play a role in the regulation of cell apoptosis, and inhibitors of its activity may be useful in the treatment of certain types of cancer.

TMPRSS11F has also been suggested as a potential biomarker for certain diseases. For example, TMPRSS11F has been shown to be involved in the regulation of cell apoptosis in various diseases, including neurodegenerative diseases and cancer. inhibitors of TMPRSS11F activity may be useful in the treatment of these diseases.

Conclusion

In conclusion, TMPRSS11F is a protein that has been shown to play a role in various physiological processes, including cell signaling, tissue repair, and inflammation. It is also a member of the trypsin-like family of enzymes and has been shown to interact with various drug molecules. These interactions may be involved in the regulation of TMPRSS11F activity and could be potential drug targets or biomarkers. Further research is needed to fully understand the biology and potential of TMPRSS11F.

Protein Name: Transmembrane Serine Protease 11F

Functions: Probable serine protease

The "TMPRSS11F Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TMPRSS11F comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

TMPRSS12 | TMPRSS13 | TMPRSS15 | TMPRSS2 | TMPRSS3 | TMPRSS4 | TMPRSS5 | TMPRSS6 | TMPRSS7 | TMPRSS9 | TMSB10 | TMSB15A | TMSB15B | TMSB4X | TMSB4XP1 | TMSB4XP2 | TMSB4XP4 | TMSB4XP8 | TMSB4Y | TMTC1 | TMTC2 | TMTC3 | TMTC4 | TMUB1 | TMUB2 | TMX1 | TMX2 | TMX2-CTNND1 | TMX3 | TMX4 | TNC | TNF | TNF receptor-associated factor (TRAF) | TNFAIP1 | TNFAIP2 | TNFAIP3 | TNFAIP6 | TNFAIP8 | TNFAIP8L1 | TNFAIP8L2 | TNFAIP8L2-SCNM1 | TNFAIP8L3 | TNFRSF10A | TNFRSF10A-DT | TNFRSF10B | TNFRSF10C | TNFRSF10D | TNFRSF11A | TNFRSF11B | TNFRSF12A | TNFRSF13B | TNFRSF13C | TNFRSF14 | TNFRSF14-AS1 | TNFRSF17 | TNFRSF18 | TNFRSF19 | TNFRSF1A | TNFRSF1B | TNFRSF21 | TNFRSF25 | TNFRSF4 | TNFRSF6B | TNFRSF8 | TNFRSF9 | TNFSF10 | TNFSF11 | TNFSF12 | TNFSF12-TNFSF13 | TNFSF13 | TNFSF13B | TNFSF14 | TNFSF15 | TNFSF18 | TNFSF4 | TNFSF8 | TNFSF9 | TNIK | TNIP1 | TNIP2 | TNIP2P1 | TNIP3 | TNK1 | TNK2 | TNK2-AS1 | TNKS | TNKS1BP1 | TNKS2 | TNMD | TNN | TNNC1 | TNNI1 | TNNI2 | TNNI3 | TNNI3K | TNNT1 | TNNT2 | TNNT3 | TNP1 | TNP2