Target Name: NRGN
NCBI ID: G4900
Review Report on NRGN Target / Biomarker Content of Review Report on NRGN Target / Biomarker
NRGN
Other Name(s): NRGN variant 2 | protein kinase C substrate | hng | NEUG(55-78) | neurogranin | Protein kinase C substrate | Neurogranin, transcript variant 2 | Calmodulin-binding protein | neurogranin (protein kinase C substrate, RC3) | Neurogranin | calmodulin-binding protein | RC3 | Ng | NEUG_HUMAN | OTTHUMP00000231529

Understanding The Role of NRGN in Neurological Disorders

Natural killer cells (NK cells) are a crucial part of the immune system, which are responsible for fighting off infections and diseases in the body. They are a type of immune cell that can detect and destroy abnormal cells, including viruses, bacteria, and cancer cells. One of the key proteins that NK cells recognize and attack is the nervous system-related gene (NRGN) variant 2.

NRGN is a gene that is expressed in many different tissues throughout the body, including the brain, spinal cord, and blood cells. It is a member of the neurotrophic factor gene family, which is a group of genes that are involved in the development and maintenance of neural tissue.NRGN has been shown to play a role in the development and progression of a number of neurological and psychiatric disorders, including multiple sclerosis, depression, and anxiety.

Despite the promising potential of NRGN as a drug target, much research is still needed to fully understand its functions and how it can be used to treat disease. In this article, we will discuss the current state of research on NRGN and its potential as a drug target.

The Importance of NRGN

NRGN is a key regulator of the nervous system, and its functions are essential for the development and maintenance of neural tissue. It is involved in the production of several key proteins that are involved in the structure and function of neural tissue, including neurotrophic factor- related proteins. These proteins help to maintain the integrity of neural tissue and ensure that it can function properly.

NRGN is also involved in the regulation of the immune system, and has been shown to play a role in the immune response against viruses and bacteria. In addition, it has been shown to be involved in the regulation of pain perception, and may be a potential target for treatments for chronic pain.

NRGN and nervous system disorders

Multiple sclerosis is a chronic and progressive disease that affects the central nervous system. It is characterized by the progressive loss of nerve cells in the brain and spinal cord, leading to a range of symptoms. The exact cause of multiple sclerosis is not known, but it is thought to involve an immune system response that attacks the protective covering of nerve cells.

NRGN has been shown to be involved in the development and progression of multiple sclerosis, and may be a potential drug target. Studies have shown that individuals with multiple sclerosis have lower levels of NRGN than those without the disease. Also, individuals with multiple sclerosis have higher levels of antibodies that are associated with the immune response and may contribute to the development of the disease.

Depression is a common mental disorder that can have a significant impact on an individual's overall well-being. It is characterized by feelings of sadness, hopelessness, and a loss of interest in activities that were previously enjoyed.

NRGN has been shown to be involved in the development and progression of depression, and may be a potential drug target. Studies have shown that individuals with depression have lower levels of NRGN than those without the disease. Also, individuals with depression have higher levels of cortisol, a hormone that is associated with stress and may contribute to the development of the disease.

Anxiety is a common mental disorder that can have a significant impact on an individual's overall well-being. It is characterized by feelings of worry, apprehension, and fear.

NRGN has been shown to be involved in the development and progression of anxiety, and may be a potential drug target. Studies have shown that individuals with anxiety have lower levels of NRGN than those without the disease. Also, individuals with anxiety have higher levels of cortisol, a hormone that is associated with stress and may contribute to the development of the disease.

NRGN as a drug target

NRGN is a potential drug target because of its involvement in the development and progression of a number of neurological and psychiatric disorders. Studies have shown that NRGN can be targeted with small molecules, such as those used to treat

Protein Name: Neurogranin

Functions: Acts as a 'third messenger' substrate of protein kinase C-mediated molecular cascades during synaptic development and remodeling. Binds to calmodulin in the absence of calcium (By similarity)

The "NRGN Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NRGN comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

NRIP1 | NRIP2 | NRIP3 | NRIP3-DT | NRIR | NRK | NRL | NRM | NRN1 | NRN1L | NRON | NRP1 | NRP2 | NRROS | NRSN1 | NRSN2 | NRSN2-AS1 | NRTN | NRXN1 | NRXN2 | NRXN2-AS1 | NRXN3 | NSA2 | NSA2P2 | NSD1 | NSD2 | NSD3 | NSDHL | NSF | NSFL1C | NSFP1 | NSG1 | NSG2 | NSL complex | NSL1 | NSMAF | NSMCE1 | NSMCE1-DT | NSMCE2 | NSMCE3 | NSMCE4A | NSMF | NSRP1 | NSUN2 | NSUN3 | NSUN4 | NSUN5 | NSUN5P1 | NSUN5P2 | NSUN6 | NSUN7 | NT5C | NT5C1A | NT5C1B | NT5C1B-RDH14 | NT5C2 | NT5C3A | NT5C3AP1 | NT5C3B | NT5CP2 | NT5DC1 | NT5DC2 | NT5DC3 | NT5DC4 | NT5E | NT5M | NTAN1 | NTAQ1 | NTF3 | NTF4 | NTHL1 | NTM | NTMT1 | NTMT2 | NTN1 | NTN3 | NTN4 | NTN5 | NTNG1 | NTNG2 | NTPCR | NTRK1 | NTRK2 | NTRK3 | NTRK3-AS1 | NTS | NTSR1 | NTSR2 | NuA4 histone acetyltransferase (HAT) complex | NUAK Family SNF1-like Kinase (nonspcified subtype) | NUAK1 | NUAK2 | NUB1 | NUBP1 | NUBP2 | NUBPL | NUCB1 | NUCB2 | NUCKS1 | Nuclear factor interleukin-3-regulated protein-like