SHANK1: A Potential Drug Target and Biomarker (G50944)

Target Name: SHANK1

NCBI ID: G50944

SHANK1

SHANK1: A Potential Drug Target and Biomarker

Somatostatin, a protein produced by the body, plays a crucial role in cell growth, development, and survival. It is a negative regulator of cell proliferation, and its levels have been linked to various diseases, including cancer. The SHANK1 protein, which is named after its gene name, has been identified as a potential drug target and biomarker for various diseases.

SHANK1 functions as a negative regulator of cell proliferation

SHANK1 is a 22-kDa protein that is expressed in various tissues of the body, including muscle, bone, liver, and pancreas. It is highly expressed in cancer cells and has been linked to the development and progression of various types of cancer. SHANK1 functions as a negative regulator of cell proliferation by inhibiting the activity of the retinoblastoma gene (Rb), which is responsible for the production of the oncogene p53.

The p53 gene is a well-known tumor suppressor gene that plays a crucial role in preventing the development and progression of cancer. It is expressed in various tissues of the body and is often mutated in cancer. The SHANK1 protein can interact with the p53 gene and prevent its activity, thereby inhibiting the growth and proliferation of cancer cells.

SHANK1 is also involved in the regulation of cell adhesion

SHANK1 is involved in the regulation of cell adhesion, which is the process by which cells stick together to form tissues and organs. It is a critical factor in the development and maintenance of tissues and organs, and its levels have been linked to various diseases, including cancer.

SHANK1 has been shown to be involved in the regulation of cell adhesion by interacting with the cadher protein, which is a transmembrane protein that is involved in cell adhesion. The cadher protein helps to maintain the integrity of the intercellular space and plays a crucial role in the development and maintenance of tissues and organs.

SHANK1 is also involved in the regulation of cell migration

SHANK1 is involved in the regulation of cell migration, which is the process by which cells move from their place of origin to their destination in the body. It is a critical factor in the development and maintenance of tissues and organs, and its levels have been linked to various diseases, including cancer.

SHANK1 has been shown to be involved in the regulation of cell migration by interacting with the vimentin protein, which is a microtubule protein that is involved in cell movement. The vimentin protein helps to maintain the integrity of the microtubules and plays a crucial role in the development and maintenance of tissues and organs.

SHANK1 is a potential drug target

SHANK1 has been identified as a potential drug target for various diseases, including cancer. Its interaction with the p53 gene and the cadher protein has been shown to contribute to its potential as a drug target. SHANK1 has also been shown to be involved in the regulation of cell adhesion and cell migration, which are important factors in the development and maintenance of tissues and organs.

In conclusion, SHANK1 is a protein that has been identified as a potential drug target and biomarker for various diseases. Its interaction with the p53 gene and the cadher protein has been shown to contribute to its potential as a drug target. Further research is needed to fully understand its role in the development and progression of cancer and other diseases.

Protein Name: SH3 And Multiple Ankyrin Repeat Domains 1

Functions: Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction

The "SHANK1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SHANK1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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