Target Name: ABHD14A
NCBI ID: G25864
Review Report on ABHD14A Target / Biomarker Content of Review Report on ABHD14A Target / Biomarker
ABHD14A
Other Name(s): Abhydrolase domain containing 14A | Protein ABHD14A | alpha/beta hydrolase domain-containing protein 14A | ABHEA_HUMAN | abhydrolase domain containing 14A | abhydrolase domain-containing protein 14A | DORZ1

ABHD14A: A Potential Drug Target and Biomarker

Introduction

ABHD14A is a protein that is expressed in various tissues and cells in the human body. It is a member of the ABH domain family, which is known for their role in the regulation of cell signaling pathways. The ABH domains are characterized by the presence of a specific amino acid sequence that is responsible for the protein's unique structure and function. ABHD14A is unique because it is expressed in the liver, which is not typically the site of protein synthesis and storage.

The Importance of ABHD14A

ABHD14A plays a critical role in the regulation of cellular processes that are essential for life. It is involved in the detoxification of harmful substances that are present in the body, as well as in the regulation of cellular signaling pathways. This protein is also involved in the development and maintenance of the liver's structure and function.

Drug Target

The potential drug targets for ABHD14A are numerous. Its involvement in cellular signaling pathways makes it a potential target for drugs that are designed to modulate cellular signaling pathways. Additionally, its role in the regulation of liver function makes it a potential target for drugs that are designed to modulate liver function.

Biomarker

ABHD14A is also potential biomarker for diseases such as hepatitis, liver cancer, and non-alcoholic steatohepatitis (NASH). The liver is a key organ that is affected by many diseases, and ABHD14A's involvement in the regulation of cellular signaling pathways makes it a potential biomarker for these diseases.

Expression and Regulation

ABHD14A is expressed in various tissues and cells in the human body, including the liver, muscle, and heart. It is primarily expressed in the liver, where it is involved in the detoxification of harmful substances and in the regulation of cellular signaling pathways. The expression of ABHD14A is regulated by several factors, including its DNA binding, protein stability, and interactions with other proteins.

ABHD14A is regulated by several different signaling pathways. One of the most well-studied pathways is the PI3K/Akt signaling pathway. This pathway is involved in the regulation of cellular signaling pathways, including the regulation of cell growth, differentiation, and survival. ABHD14A is known to be involved in the regulation of this pathway, and its absence has been shown to have negative effects on cellular signaling.

Another pathway that is involved in the regulation of ABHD14A is the TGF-β signaling pathway. This pathway is involved in the regulation of cell growth, differentiation, and survival, as well as in the regulation of cell-cell and cell-tissue interactions. ABHD14A is also known to be involved in the regulation of this pathway, and its deletion has been shown to have negative effects on cellular signaling.

Conclusion

ABHD14A is a protein that is expressed in various tissues and cells in the human body. It is a member of the ABH domain family and plays a critical role in the regulation of cellular processes that are essential for life. Its involvement in cellular signaling pathways makes it a potential target for drugs that are designed to modulate these pathways. Additionally, its role in the regulation of liver function makes it a potential target for drugs that are designed to modulate liver function. Furthermore, ABHD14A is also potential biomarker for diseases such as hepatitis, liver cancer, and non-alcoholic steatohepatitis (NASH). Its expression is regulated by several signaling pathways, including the PI3K/Akt and TGF-β signaling pathways. Therefore, ABHD14A is a promising target for future drug development.

Protein Name: Abhydrolase Domain Containing 14A

Functions: Possible role in granule neuron development

The "ABHD14A Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ABHD14A comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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