GPR84: A Drug Target / Disease Biomarker (G53831)

Target Name: GPR84

NCBI ID: G53831

GPR84

GPR84: A Drug Target / Disease Biomarker

GPR84 is a G protein-coupled receptor (GPCR) that is expressed in various tissues and cells throughout the body. It is involved in a wide range of physiological processes, including sensory perception, neurotransmitter signaling, and hormone regulation. As a result, GPR84 has been identified as a potential drug target and a biomarker for various diseases.

GPR84 is a member of the GPCR family, which includes over 700 different genes that encode for GPCRs. These genes are expressed in a wide range of tissues and cells, including neurons, muscle cells, heart cells, and immune cells. GPR84 is a single gene that encodes for a protein that is similar to other GPCRs. It has 114 amino acid residues and a calculated molecular weight of 13.9 kDa.

GPR84 is expressed in various tissues and cells throughout the body, including the brain, spinal cord, heart, kidneys, and pancreas. It is also expressed in the testes and ovaries, which may be important for sexual function and reproduction.

GPR84 is involved in a wide range of physiological processes that are important for the health and function of the body. It is involved in sensory perception, which is the ability to sense the world around us. GPR84 is thought to be involved in the sense of touch, as well as in the perception of pain and inflammation.

GPR84 is also involved in neurotransmitter signaling, which is the process by which nerve cells communicate with each other. It is a critical receptor for several neurotransmitters, including dopamine, serotonin, and GABA. Dopamine is a neurotransmitter that is involved in the pleasure and reward aspects of behavior, while serotonin is involved in mood regulation and appetite. GPR84 is also involved in the regulation of pain, which is important for the body's ability to heal and recover from injuries and illnesses.

In addition to its role in sensory perception and neurotransmitter signaling, GPR84 is also involved in hormone regulation. It is a critical receptor for several hormones, including testosterone and estrogen. Testosterone is a hormone that is involved in male sexual function and development, while estrogen is a hormone that is involved in female sexual function and development. GPR84 is also involved in the regulation of insulin secretion, which is important for maintaining blood sugar levels.

As a result of its involvement in these important processes, GPR84 has been identified as a potential drug target. Many diseases, including diabetes, pain, and neurodegenerative disorders, are caused by the disruption of normal cellular processes that are controlled by GPCRs. By targeting GPR84, drugs can potentially improve cellular processes and reduce the risk of disease.

GPR84 has also been identified as a potential biomarker for several diseases. For example, it has been used as a biomarker for cancer, as it is often overexpressed in cancer cells compared to normal cells. In addition, GPR84 has been used as a biomarker for neurodegenerative disorders, as it is often expressed in the brains of people with these disorders.

In conclusion, GPR84 is a GPCR that is involved in a wide range of physiological processes throughout the body. It has been identified as a potential drug target and biomarker for several diseases. Further research is needed to fully understand the role of GPR84 in these processes and to develop effective treatments.

Protein Name: G Protein-coupled Receptor 84

Functions: Receptor for medium-chain free fatty acid (FFA) with carbon chain lengths of C9 to C14. Capric acid (C10:0), undecanoic acid (C11:0) and lauric acid (C12:0) are the most potent agonists. Not activated by short-chain and long-chain saturated and unsaturated FFAs. Activation by medium-chain free fatty acid is coupled to a pertussis toxin sensitive G(i/o) protein pathway. May have important roles in processes from fatty acid metabolism to regulation of the immune system

The "GPR84 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GPR84 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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