Unlocking The Potential of UBA6-DT as A Drug Target Or Biomarker

Target Name: UBA6-DT

NCBI ID: G550112

UBA6-DT

Other Name(s): UBA6-AS1 | UBA6 divergent transcript

Unlocking The Potential of UBA6-DT as A Drug Target Or Biomarker

UBA6-DT, also known as UBA6-AS1, is a protein that is expressed in various tissues of the body, including the brain, heart, and liver. It is a member of the UBA6 family of proteins, which are known for their role in intracellular signaling. UBA6-DT has been shown to play a role in a variety of biological processes, including cell signaling, inflammation, and metabolism. As a result, UBA6-DT has potential as a drug target or biomarker.

The UBA6 family of proteins is characterized by the presence of a unique N-terminal domain that consists of a conserved core sequence and a variable C-terminal region. The conserved core sequence is composed of a series of amino acids that are highly conserved across different species, while the variable C-terminal region is unique to each protein. The variable C-terminal region typically includes a protein-destination domain, which is involved in the interaction between the protein and other cellular components.

UBA6-DT is a 12kDa protein that is expressed in the brain, heart, and liver. It is predominantly localized to the endoplasmic reticulum (ER), a protein-sorting and delivery system that is responsible for transporting proteins from the cytoplasm to the ER. The ER is a transmembrane system that separates the cytoplasm from the ER lumen, and it is filled with a variety of proteins that play important roles in cellular signaling and metabolism.

UBA6-DT has been shown to play a role in several important biological processes. For example, it has been shown to be involved in the regulation of cell signaling by intracellular signaling pathways. UBA6-DT has been shown to interact with several different signaling molecules, including TGF-β, NF-kappa-B, and MAPK. These interactions are important for the regulation of cellular processes such as cell growth, differentiation, and inflammation.

In addition to its role in intracellular signaling, UBA6-DT has also been shown to be involved in the regulation of inflammation. UBA6-DT has been shown to play a role in the regulation of inflammatory responses, including the regulation of the production of pro-inflammatory cytokines. This role is important for the regulation of tissue repair and regeneration following injury or inflammation.

UBA6-DT has also been shown to be involved in the regulation of metabolism and energy homeostasis. For example, UBA6-DT has been shown to interact with the protein p53, which is involved in the regulation of DNA damage repair. This interaction is important for the regulation of cell cycle progression and the regulation of DNA damage repair.

Given its role in several important biological processes, UBA6-DT has potential as a drug target or biomarker. For example, UBA6-DT has been shown to interact with several different signaling molecules, including TGF-β, NF-kappa-B, and MAPK. This suggests that it may be a useful target for small molecules that can modulate these signaling pathways. Additionally, UBA6-DT has been shown to play a role in the regulation of cell signaling and inflammation, which may make it a useful target for drugs that can modulate these processes.

In conclusion, UBA6-DT is a protein that is expressed in various tissues of the body and has been shown to play a role in several important biological processes, including cell signaling, inflammation, and metabolism. Its unique N-terminal domain and variable C-terminal region make it a potential target for small molecules that can modulate these processes. Further research is needed to fully understand the role of UBA6-DT in cellular signaling and to determine its potential as a drug target or biomarker.

Protein Name: UBA6 Divergent Transcript

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•   general information;
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•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
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•   pharmacochemistry experiments;
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The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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