Histone 2: A Protein Regulator of Cellular Processes (G554313)

Target Name: H4C15

NCBI ID: G554313

H4C15

Other Name(s): histone 2, H4b | Histone H4 | HIST1H4E | H4 clustered histone 15, transcript variant 1 | H4FO | H4C14 | HIST1H4H | HIST1H4J | translation initiation factor IF-2-like | H4C8 | H4 clustered histone 15 | HIST1H4A | H4_HUMAN | H4C12 | H4C11 | H4C9 | HIST4H4 | histone cluster 2, H4b | H4/o | H4C5 | HIST2H4A | HIST2H4B | H4C6 | H4C16 | H4C3 | histone cluster 2 H4 family member b | H4C1 | H4/O | HIST1H4B | H4C4 | HIST1H4I | H4C13 | HIST1H4D | HIST1H4L | HIST1H4K | H4C2 | HIST1H4F | H4C15 variant 1 | HIST1H4C | H4-16

Histone 2: A Protein Regulator of Cellular Processes

Histone 2, also known as H2 or H4b, is a protein that plays a crucial role in the regulation of gene expression and cell behavior. It is a key component of the histone complex, which is a protein-protein interaction network that makes up the nucleosome, the basic unit of chromatin. Histone 2 is composed of four subunits, each with a different size and function.

One of the subunits of histone 2 is histone B (H4b), which is a 20-kDa protein that is composed of 196 amino acid residues. H4b is involved in the regulation of gene expression by binding to specific DNA sequences and affecting the activity of transcription factors. It has been shown to play a role in the regulation of cell growth, differentiation, and apoptosis.

Another subunit of histone 2 is histone A (H1), which is a 17-kDa protein that is composed of 164 amino acid residues. H1 is involved in the regulation of gene expression by binding to specific DNA sequences and affecting the activity of transcription factors. It has been shown to play a role in the regulation of cell growth, differentiation, and apoptosis.

Histone 2 has been shown to play a role in the regulation of a wide range of cellular processes, including cell growth, differentiation, and apoptosis. It is a potential drug target because of its involvement in these processes and its ability to interact with specific DNA sequences.

One of the potential benefits of targeting histone 2 is its potential to treat a wide range of diseases. For example, histone 2 has been shown to be involved in the regulation of cancer cell growth and has been linked to the development of certain types of cancer. Additionally, histone 2 has been shown to play a role in the regulation of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease.

Another potential benefit of targeting histone 2 is its potential to treat genetic disorders. For example, histone 2 has been shown to play a role in the regulation of Down syndrome, a genetic disorder that affects approximately 1 in 2,000 people. Additionally, histone 2 has been shown to play a role in the regulation of individuals with Fragile X syndrome, a genetic disorder that affects approximately 1 in 8,000 people.

Targeting histone 2 may also have potential benefits in the treatment of other diseases and conditions. For example, it has been shown to play a role in the regulation of skin aging and has been linked to the development of certain types of skin diseases, such as acne and rosacea. Additionally, histone 2 has been shown to play a role in the regulation of hair growth and has been linked to the development of certain types of hair diseases, such as dandruff.

In conclusion, histone 2 is a protein that plays a crucial role in the regulation of gene expression and cell behavior. It is composed of four subunits, including histone B and histone A, and has been shown to play a role in the regulation of a wide range of cellular processes, including cell growth, differentiation, and apoptosis. Targeting histone 2 may have potential benefits in the treatment of a wide range of diseases and conditions.

Protein Name: H4 Clustered Histone 15

Functions: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling

The "H4C15 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about H4C15 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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