Target Name: NOP10
NCBI ID: G55505
Review Report on NOP10 Target / Biomarker Content of Review Report on NOP10 Target / Biomarker
NOP10
Other Name(s): Nucleolar protein 10 | NOLA3 | NOP10 ribonucleoprotein | nucleolar protein family A member 3 | Nucleolar protein family A member 3 | snoRNP protein NOP10 | NOP10_HUMAN | H/ACA ribonucleoprotein complex subunit 3 | NOP10P | nucleolar protein 10 | SnoRNP protein NOP10 | NOP10 ribonucleoprotein homolog | nucleolar protein family A, member 3 (H/ACA small nucleolar RNPs) | DKCB1 | MGC70651 | homolog of yeast Nop10p

NOP10: A Transmembrane Protein Involved in Cellular Processes and Disease

Nucleolar protein 10 (NOP10) is a protein that is expressed in a variety of cell types, including neurons, muscle cells, and red blood cells. It is a member of the nucleolar protein (NOP) family, which is a group of proteins that are involved in the maintenance and organization of the nuclear genome.

NOP10 is unique among the NOP proteins in that it is a transmembrane protein. This means that it spans the cell membrane and is involved in various processes that are specific to the cell membrane environment. NOP10 is also unique in that it has a unique signal transduction mechanism.

The NOP10 protein is involved in the regulation of various cellular processes that are important for cell growth, including cell division, cytoskeletal organization, and chromatin structure. It is also involved in the regulation of cell survival and in the development and progression of various diseases, including cancer.

Due to its unique role in cell biology, NOP10 has been identified as a potential drug target. Researchers are currently studying the potential mechanisms of NOP10 and are exploring ways to use it as a therapeutic agent.

One of the main research efforts is focused on understanding the function of NOP10 in cancer. Studies have shown that NOP10 is often overexpressed in various types of cancer, and that it is involved in the regulation of cell proliferation and survival.

In addition to its role in cancer, NOP10 is also involved in the regulation of normal cellular processes, including cell growth, differentiation, and survival. This makes it an attractive target for researchers who are studying the mechanisms of normal cell biology.

Another area of research is the study of the potential uses of NOP10 as a drug. Studies have shown that NOP10 can be used to inhibit the growth of cancer cells in a variety of models, including cell culture and animal models. In addition, NOP10 has been shown to have anti-inflammatory effects and to have a positive impact on the immune system.

Overall, NOP10 is a unique and promising protein that has the potential to be a drug target or biomarker. Further research is needed to fully understand its role in cell biology and its potential as a therapeutic agent.

Protein Name: NOP10 Ribonucleoprotein

Functions: Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ('psi') residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme

The "NOP10 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NOP10 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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