Discovering The IQUB Protein: A Potential Drug Target and Biomarker

Target Name: IQUB

NCBI ID: G154865

IQUB

Other Name(s): IQ motif and ubiquitin domain containing | IQ motif and ubiquitin domain containing, transcript variant 1 | IQ and ubiquitin-like domain-containing protein | IQUB_HUMAN | IQUB variant 1

Discovering The IQUB Protein: A Potential Drug Target and Biomarker

The IQUB protein, also known as IQUB-TIM-DM domain containing protein 1, is a protein that plays a crucial role in the regulation of protein-protein interactions (PPIs) and is a potential drug target and biomarker. IQUB is a member of the IQ motif family, which is known for their ability to interact with various protein partners, including ubiquitin, to control protein stability and localization.

The IQUB protein was first identified as a gene that was expressed in a variety of tissues and organs, including brain, heart, and muscle. It is also known to be involved in the regulation of cellular processes such as cell adhesion, migration, and survival.

One of the unique features of IQUB is its ability to interact with the ubiquitin protein, which is a key regulator of protein stability and localization in the cell. This interaction between IQUB and ubiquitin allows IQUB to influence the stability and localization of other proteins, including target proteins that are involved in cellular processes such as cell adhesion, migration, and survival.

The IQUB protein is also involved in the regulation of the ubiquitin-protein interactions by creating a protein-protein interaction complex with the ubiquitin protein. This interaction between IQUB and ubiquitin allows IQUB to influence the stability and localization of other proteins, including target proteins that are involved in cellular processes such as cell adhesion, migration, and survival.

In addition to its role in the regulation of protein-protein interactions, IQUB is also involved in the regulation of protein stability and localization in the cell. IQUB is known to play a role in the regulation of the stability of the protein tyrosine, which is a key protein involved in the regulation of cellular processes such as cell adhesion, migration, and survival.

The IQUB protein is also involved in the regulation of the localization of the protein endoplasmic reticulum (ER), which is a structure that transports proteins from the cytoplasm to the endoplasmic reticulum. IQUB is known to play a role in the regulation of the localization of the protein syntaxin, which is a key protein involved in the regulation of the localization of other proteins in the ER.

In conclusion, the IQUB protein is a member of the IQ motif family and is involved in the regulation of protein-protein interactions, protein stability and localization in the cell. Its ability to interact with the ubiquitin protein makes it a potential drug target and biomarker. Further research is needed to fully understand the role of IQUB in cellular processes and its potential as a drug.

Protein Name: IQ Motif And Ubiquitin Domain Containing

Functions: Adapter protein that anchors the radial spoke 1 (RS1) complex to the A microtubule of outer doublet microtubules in axonemes (PubMed:36355624). The triple radial spokes (RS1, RS2 and RS3) are required to modulate beating of the sperm flagellum (PubMed:36355624). May play a role in inhibiting signaling via MAPK1/ERK2 and MAPK3/ERK1 (PubMed:36355624). Additionally, may play a role in the functioning of cilia (By similarity). Not required for the functioning of tracheal or ependymal cilia (By similarity)

The "IQUB Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about IQUB comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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