IQCE: A Protein Regulating Cell Signaling, Inflammation, Cell Adhesion and Apoptosis

Target Name: IQCE

NCBI ID: G23288

IQCE

IQCE: A Protein Regulating Cell Signaling, Inflammation, Cell Adhesion and Apoptosis

IQCE (PAPA7) is a protein that is expressed in various tissues throughout the body. It is a member of the PAPA7 gene family, which is known for its role in cell signaling and inflammation. IQCE has been shown to play a role in the development and progression of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. As a result, IQCE has generated a lot of interest as a potential drug target or biomarker.

One of the key functions of IQCE is its role in the regulation of cell signaling pathways. IQCE has been shown to play a negative role in the regulation of the PI3K/Akt signaling pathway, which is involved in various cellular processes, including cell growth, survival, and angiogenesis. This negative regulation of PI3K/Akt signaling pathway by IQCE has implications for the development of cancer, as increased PI3K/Akt signaling can contribute to the growth and survival of cancer cells.

Another function of IQCE is its role in the regulation of inflammation. IQCE has been shown to play a positive role in the regulation of the NF-kappa-B signaling pathway, which is involved in the regulation of various cellular processes, including inflammation, immune response, and cell signaling. This positive regulation of NF-kappa-B signaling pathway by IQCE has implications for the development of inflammatory diseases, as decreased NF-kappa-B signaling can contribute to the regulation of inflammation.

In addition to its role in cell signaling and inflammation, IQCE has also been shown to play a role in the regulation of cell adhesion. IQCE has been shown to play a negative role in the regulation of the cadherin gene, which is involved in cell adhesion and the development of cancer. This negative regulation of cadherin gene by IQCE has implications for the development of cancer, as decreased cadherin gene expression can contribute to the development of cancer cells.

IQCE has also been shown to play a role in the regulation of cell apoptosis, which is the process by which cells undergo programmed cell death. IQCE has been shown to play a positive role in the regulation of cell apoptosis, as it has been shown to promote the survival of certain cell types by regulating their apoptosis. This positive regulation of cell apoptosis by IQCE has implications for the development of neurodegenerative diseases, as increased cell apoptosis can contribute to the development of these diseases.

Finally, IQCE has also been shown to play a role in the regulation of tissue repair and regeneration. IQCE has been shown to play a positive role in the regulation of tissue repair and regeneration, as it has been shown to promote the growth and survival of certain tissues after injury or disease. This positive regulation of tissue repair and regeneration by IQCE has implications for the development of wound healing, tissue engineering, and regenerative medicine.

In conclusion, IQCE is a protein that plays a critical role in the regulation of various cellular processes in the body. Its negative regulation of PI3K/Akt signaling pathway, NF-kappa-B signaling pathway, cadherin gene, and cell apoptosis have implications for the development of cancer, neurodegenerative diseases, and autoimmune disorders. In addition, IQCE has also been shown to play a positive role in the regulation of tissue repair and regeneration. As a result, IQCE has generated a lot of interest as a potential drug target or biomarker. Further research is needed to fully understand the role of IQCE in the development and progression of various diseases.

Protein Name: IQ Motif Containing E

Functions: Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling (By similarity). Required for proper limb morphogenesis (PubMed:28488682)

The "IQCE Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about IQCE comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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