Target Name: IQGAP2
NCBI ID: G10788
Review Report on IQGAP2 Target / Biomarker Content of Review Report on IQGAP2 Target / Biomarker
IQGAP2
Other Name(s): IQGAP2 variant 1 | IQGA2_HUMAN | OTTHUMP00000222010 | Ras GTPase-activating-like protein IQGAP2 | OTTHUMP00000222013 | IQ motif containing GTPase activating protein 2 | IQ motif containing GTPase activating protein 2, transcript variant 1 | Ras GTPase-activating-like protein IQGAP2 isoform 1

IQGAP2: The Potential Drug Target and Biomarker

IQGAP2, a gene that encodes a protein known as IQGAP2, has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative disorders, and psychiatric conditions. IQGAP2 has been shown to play a crucial role in multiple cellular processes that are involved in cell growth, differentiation, and survival. In this article, we will discuss the potential drug target and biomarker properties of IQGAP2, as well as its current status in research and its potential impact on human health.

Potential Drug Target

IQGAP2 has been identified as a potential drug target due to its involvement in various cellular processes that are associated with the development and progression of various diseases. One of the main reasons for its potential as a drug target is its role in cell signaling pathways. IQGAP2 has been shown to be involved in several signaling pathways that are involved in cancer progression, including the PI3K/Akt signaling pathway, the TGF-β signaling pathway, and the NF-kappa-B signaling pathway.

In addition to its involvement in these signaling pathways, IQGAP2 has also been shown to be involved in the regulation of cell adhesion and migration. This is important because changes in cell adhesion and migration have been implicated in the development and progression of various diseases, including cancer.

Potential Biomarker

IQGAP2 has also been identified as a potential biomarker for various diseases due to its involvement in the regulation of cellular processes that are involved in disease progression. For example, IQGAP2 has been shown to be involved in the regulation of angiogenesis, which is the process by which new blood vessels are formed. This is important because changes in angiogenesis have been implicated in the development and progression of various diseases, including cardiovascular disease and cancer.

In addition to its involvement in angiogenesis, IQGAP2 has also been shown to be involved in the regulation of cell survival and proliferation. This is important because changes in cell survival and proliferation have been implicated in the development and progression of various diseases, including neurodegenerative disorders.

Current Status in Research

IQGAP2 is currently being studied in various clinical trials and research studies as a potential drug target and biomarker. For example, a trial is underway to evaluate the efficacy and safety of a drug that targets IQGAP2 in combination with chemotherapy for the treatment of breast cancer. Other studies are are focused on the regulation of angiogenesis, cell survival and proliferation, and the role of IQGAP2 in disease progression.

Impact on Human Health

IQGAP2 has the potential to make a significant impact on human health by targeting and treating various diseases that are associated with changes in cellular processes. The identification of IQGAP2 as a potential drug target and biomarker is a promising development in the field of pharmacology, and further research is needed to understand its full potential as a therapeutic agent.

Conclusion

In conclusion, IQGAP2 is a gene that encodes a protein that plays a crucial role in multiple cellular processes that are involved in cell growth, differentiation, and survival. Its potential as a drug target and biomarker has been identified in various diseases, including cancer, neurodegenerative disorders, and psychiatric conditions. Further research is needed to understand its full potential as a therapeutic agent and to develop safe and effective treatments based on its target.

Protein Name: IQ Motif Containing GTPase Activating Protein 2

Functions: Binds to activated CDC42 and RAC1 but does not seem to stimulate their GTPase activity. Associates with calmodulin

The "IQGAP2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about IQGAP2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

IQGAP3 | IQSEC1 | IQSEC2 | IQSEC3 | IQSEC3P3 | IQUB | IRAG1 | IRAG1-AS1 | IRAG2 | IRAK1 | IRAK1BP1 | IRAK2 | IRAK3 | IRAK4 | IREB2 | IRF1 | IRF1-AS1 | IRF2 | IRF2BP1 | IRF2BP2 | IRF2BPL | IRF3 | IRF4 | IRF5 | IRF6 | IRF7 | IRF8 | IRF9 | IRGC | IRGM | IRGQ | IRS1 | IRS2 | IRS4 | IRX1 | IRX2 | IRX2-DT | IRX3 | IRX4 | IRX5 | IRX6 | ISCA1 | ISCA1P1 | ISCA2 | ISCU | ISG15 | ISG20 | ISG20L2 | ISL1 | ISL1-DT | ISL2 | ISLR | ISLR2 | ISM1 | ISM2 | ISOC1 | ISOC2 | Isocitrate dehydrogenase 3 (NAD+) | Isocitrate dehydrogenases | Isoleucyl-tRNA synthetase | IST1 | ISWI Chromatin Remodeling Complex | ISX | ISY1 | ISY1-RAB43 | ISYNA1 | ITCH | ITFG1 | ITFG2 | ITFG2-AS1 | ITGA1 | ITGA10 | ITGA11 | ITGA2 | ITGA2B | ITGA3 | ITGA4 | ITGA5 | ITGA6 | ITGA6-AS1 | ITGA7 | ITGA8 | ITGA9 | ITGAD | ITGAE | ITGAL | ITGAM | ITGAV | ITGAX | ITGB1 | ITGB1BP1 | ITGB1BP2 | ITGB1P1 | ITGB2 | ITGB2-AS1 | ITGB3 | ITGB3BP | ITGB4 | ITGB5 | ITGB6