Target Name: PRKAR2B
NCBI ID: G5577
Review Report on PRKAR2B Target / Biomarker Content of Review Report on PRKAR2B Target / Biomarker
PRKAR2B
Other Name(s): KAP3_HUMAN | cAMP-dependent protein kinase type II-beta regulatory subunit | WUGSC:H_RG363E19.2 | cAMP-dependent protein kinase type II-beta regulatory chain | CAMP-dependent protein kinase type II-beta regulatory subunit | RII-BETA | protein kinase, cAMP-dependent, regulatory subunit type II beta | protein kinase, cAMP-dependent, regulatory, type II, beta | H_RG363E19.2 | Protein kinase cAMP-dependent type II regulatory subunit beta | protein kinase cAMP-dependent type II regulatory subunit beta | PRKAR2

PRKAR2B: A Protein Regulating Cellular Processes

PRKAR2B (KAP3_HUMAN) is a protein that is expressed in various tissues of the human body, including the brain, heart, liver, and pancreas. Its full name is PRKAR2B (KAP3) Homolog B, and it is a member of the PRKAR2 family of proteins.

PRKAR2B is known for its role in the regulation of cellular processes that are important for the development and maintenance of tissues. It has been shown to play a role in the development of various diseases, including cancer, neurodegenerative diseases, and autoimmune diseases.

One of the key functions of PRKAR2B is its role in the regulation of cell proliferation. PRKAR2B has been shown to play a negative role in the growth and proliferation of cancer cells. It has been shown to inhibit the growth of cancer cells in cell culture and in animal models of cancer.

Another function of PRKAR2B is its role in the regulation of cell apoptosis, or cell death. PRKAR2B has been shown to play a role in the regulation of cell apoptosis in various tissues, including the brain. It has been shown to promote the programmed cell death that occurs in neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease.

In addition to its role in cell proliferation and apoptosis, PRKAR2B is also known for its role in the regulation of cellular signaling pathways. It has been shown to play a role in the regulation of several signaling pathways that are important for the development and maintenance of tissues.

One of the signaling pathways that is regulated by PRKAR2B is the TGF-β pathway. TGF-β is a signaling pathway that is involved in the regulation of cellular growth, differentiation, and survival. It has been shown that PRKAR2B plays a role in the regulation of TGF-β signaling pathway in various tissues.

Another signaling pathway that is regulated by PRKAR2B is the PI3K/AKT signaling pathway. PI3K is a protein that is involved in the regulation of cellular signaling pathways, including the TGF-β pathway. AKT is a protein that is involved in the regulation of cellular signaling pathways, including the TGF-β pathway. It has been shown that PRKAR2B plays a role in the regulation of PI3K/AKT signaling pathway in various tissues.

In conclusion, PRKAR2B (KAP3_HUMAN) is a protein that is expressed in various tissues of the human body. It plays a role in the regulation of cellular processes that are important for the development and maintenance of tissues. PRKAR2B is a potential drug target and may be useful in the treatment of various diseases.

Protein Name: Protein Kinase CAMP-dependent Type II Regulatory Subunit Beta

Functions: Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase

The "PRKAR2B Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PRKAR2B comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

PRKCA | PRKCA-AS1 | PRKCB | PRKCD | PRKCE | PRKCG | PRKCH | PRKCI | PRKCQ | PRKCQ-AS1 | PRKCSH | PRKCZ | PRKCZ-AS1 | PRKD1 | PRKD2 | PRKD3 | PRKDC | PRKG1 | PRKG1-AS1 | PRKG2 | PRKG2-AS1 | PRKN | PRKRA | PRKRIP1 | PRKX | PRKXP1 | PRKY | PRL | PRLH | PRLHR | PRLR | PRM1 | PRM2 | PRM3 | PRMT1 | PRMT2 | PRMT3 | PRMT5 | PRMT5-DT | PRMT6 | PRMT7 | PRMT8 | PRMT9 | PRNCR1 | PRND | PRNP | PRNT | Pro-Neuregulin | PROB1 | PROC | PROCA1 | PROCR | PRODH | PRODHLP | Prohibitin | PROK1 | PROK2 | Prokineticin Receptor (PK-R) | PROKR1 | PROKR2 | Prolactin receptor (isoform 1) | Prolyl 4-hydroxylase | PROM1 | PROM2 | PROP1 | Propionyl-CoA Carboxylase | PRORP | PRORSD1P | PRORY | PROS1 | PROS2P | PROSER1 | PROSER2 | PROSER2-AS1 | PROSER3 | Prostaglandin EP Receptor | Prostaglandin synthase | Prostanoid Receptor | Prostanoid TP receptor | Proteasome 20S | Proteasome 26S | Proteasome Complex | Protein arginine N-methyltransferase | Protein disulfide-isomerase | Protein farnesyltransferase | Protein geranylgeranyltransferase type II | Protein kinase C | Protein Kinase D (PKD) | Protein kinase N | Protein NDRG2 (isoform a) | Protein Phosphatase | Protein Phosphatase 2A | Protein Phosphatase 2B | Protein phosphatase 6 | Protein phosphatase-1 | Protein transport protein Sec61 complex | Protein Tyrosine Phosphatase (PTP) | Protein Tyrosine Phosphatase Type IVA | Protein-Synthesizing GTPase (Elongation Factor) | Protocadherin