Target Name: PTPRC
NCBI ID: G5788
Review Report on PTPRC Target / Biomarker Content of Review Report on PTPRC Target / Biomarker
PTPRC
Other Name(s): Protein tyrosine phosphatase, receptor type, c polypeptide | Protein tyrosine phosphatase, receptor type, C, transcript variant 5 | LY5 | protein tyrosine phosphatase receptor type C | PTPRC variant 1 | Receptor-type tyrosine-protein phosphatase C (isoform 5) | SCID due to PTPRC deficiency | Receptor-type tyrosine-protein phosphatase C (isoform 2) | CD45 | PTPRC variant 2 | Receptor-type protein tyrosine phosphatase C (CD45) | Protein tyrosine phosphatase, receptor type, C (CD45) | PTPRC_HUMAN | B220 | CD45 antigen | T200 leukocyte common antigen | Leukocyte common antigen | GP180 | Receptor-type tyrosine-protein phosphatase C (isoform 1) | L-CA | LCA | PTPRC variant 5 | protein tyrosine phosphatase, receptor type, c polypeptide | IMD105 | Protein tyrosine phosphatase receptor type C, transcript variant 1 | CD45R | T200 glycoprotein | Receptor-type tyrosine-protein phosphatase C | receptor-type tyrosine-protein phosphatase C | Protein tyrosine phosphatase receptor type C, transcript variant 2 | T200

Phosphatidyl Tyrosine Protein Tyrosine Phosphatase: Drug Target and Cellular Process Regulator

Protein tyrosine phosphatase (PTPRC), also known as protein tyrosine phosphatase receptor type C (PTPRC receptor type C), is a protein that is involved in many different cellular processes in the body. It is a protein that can catalyze the removal of phosphate groups from tyrosine residues on other proteins, which is important for regulating various cellular signaling pathways. There are several different isoforms of the PTPRC, and each of them has a different function in the body.

One of the well-studied isoforms of the PTPRC is the C-type, which is also known as the alpha isoform. This isoform is primarily expressed in the brain and is involved in the regulation of many different signaling pathways, including those that are involved in the development and progression of neurodegenerative diseases.

One of the things that makes the PTPRC such an attractive drug target is its ability to interact with a wide range of molecules. This is because the PTPRC has multiple different binding sites on the same protein, which allows it to interact with a variety of different molecules. This means that it can be used to target multiple different molecules with a single drug, which can be more effective than targeting each molecule individually.

Another reason why the PTPRC is an attractive drug target is its role in the regulation of cellular signaling pathways. As mentioned earlier, the PTPRC is involved in the regulation of many different signaling pathways, including those that are involved in the development and progression of neurodegenerative diseases. By targeting the PTPRC, researchers can potentially develop new treatments for these diseases.

In addition to its role in signaling pathways, the PTPRC is also involved in the regulation of many different cellular processes. For example, it is involved in the regulation of cell division, cell signaling, and cell adhesion. This makes it an important protein that can be used to study a wide range of cellular processes in the body.

Overall, the PTPRC is a protein that has many different functions in the body, and it is an attractive drug target due to its ability to interact with a wide range of different molecules and its role in the regulation of many different cellular processes. Further research is needed to fully understand the role of the PTPRC in the body and its potential as a drug target.

Protein Name: Protein Tyrosine Phosphatase Receptor Type C

Functions: Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity)

The "PTPRC Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PTPRC comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

PTPRCAP | PTPRD | PTPRE | PTPRF | PTPRG | PTPRH | PTPRJ | PTPRK | PTPRM | PTPRN | PTPRN2 | PTPRN2-AS1 | PTPRO | PTPRQ | PTPRR | PTPRS | PTPRT | PTPRU | PTPRVP | PTPRZ1 | PTRH1 | PTRH2 | PTRHD1 | PTS | PTTG1 | PTTG1IP | PTTG2 | PTTG3P | PTX3 | PTX4 | PUDP | PUDPP2 | PUF60 | PUM1 | PUM2 | PUM3 | PURA | PURB | PURG | PURPL | PUS1 | PUS10 | PUS3 | PUS7 | PUS7L | PUSL1 | Putative POM121-like protein 1 | Putative uncharacterized protein C12orf63 | PVALB | PVALEF | PVR | PVRIG | PVT1 | PWAR1 | PWAR4 | PWAR5 | PWAR6 | PWARSN | PWP1 | PWP2 | PWRN1 | PWRN2 | PWRN3 | PWWP2A | PWWP2B | PWWP3A | PWWP3B | PXDC1 | PXDN | PXDNL | PXK | PXMP2 | PXMP4 | PXN | PXN-AS1 | PXT1 | PXYLP1 | PYCARD | PYCR1 | PYCR2 | PYCR3 | PYDC1 | PYDC2 | PYDC2-AS1 | PYGB | PYGL | PYGM | PYGO1 | PYGO2 | PYHIN1 | PYM1 | PYROXD1 | PYROXD2 | Pyruvate Dehydrogenase Complex | Pyruvate dehydrogenase kinase | Pyruvate Kinase | PYY | PYY2 | PZP | QARS1