Target Name: WFDC1
NCBI ID: G58189
Review Report on WFDC1 Target / Biomarker Content of Review Report on WFDC1 Target / Biomarker
WFDC1
Other Name(s): WFDC1 variant 1 | WAP four-disulfide core domain 1 homolog | WAP four-disulfide core domain 1, transcript variant 1 | ps20 growth inhibitor | Prostate stromal protein ps20 | PS20 | prostate stromal protein ps20 | WAP four-disulfide core domain protein 1 (isoform 1) | WFDC1_HUMAN | uncharacterized LOC105376777 | WAP four-disulfide core domain 1 | WAP four-disulfide core domain protein 1

WFDC1: A Potential Drug Target and Biomarker for Various Diseases

WFDC1 (WFDC1 variant 1) is a protein that is expressed in various tissues of the body, including the brain, heart, liver, and kidneys. It is a member of the WFDC (Wnt-Factor Determinant) family, which is known for its role in development and maintenance of tissues during embryonic development. WFDC1 has been shown to play a role in the development and progression of various diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases.

The WFDC1 protein has been identified as a potential drug target or biomarker due to its unique structure and its involvement in several disease processes. In this article, we will discuss the biology of WFDC1, its potential drug target status, and its potential as a biomarker for various diseases.

Biography of WFDC1

WFDC1 is a 21-kDa protein that is expressed in various tissues of the body, including the brain, heart, liver, and kidneys. It is a member of the WFDC (Wnt-Factor Determinant) family, which is composed of six structurally similar genes (WFDC1-6) that are involved in the development and maintenance of tissues during embryonic development.

WFDC1 is a transmembrane protein that is expressed in the cytoplasm of various cell types. It has a unique structure that consists of a long extracellular domain, a short transmembrane domain, and an intracellular tail. The extracellular domain of WFDC1 contains a series of repeats that are involved in the formation of a complex with other proteins, including the Wnt receptor.

The transmembrane domain of WFDC1 is made up of a variable number of transmembrane伪-helical subunits that are involved in the formation of the transmembrane region. The intracellular tail of WFDC1 is composed of a series of amino acids that are involved in the stability and localization of the protein within the cell.

Potential Drug Target Status

WFDC1 has been shown to play a role in the development and progression of various diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases. Its unique structure and its involvement in several disease processes have made it an attractive target for drug development.

One of the potential reasons for WFDC1's potential as a drug target is its involvement in the development and progression of cancer. WFDC1 has been shown to be involved in the regulation of cell growth and has been shown to play a role in the development of various types of cancer. For example, studies have shown that high levels of WFDC1 are associated with the development of breast cancer and that inhibition of WFDC1 has been shown to be effective in treating breast cancer.

Another potential reason for WFDC1's potential as a drug target is its involvement in neurodegenerative diseases. WFDC1 has been shown to be involved in the development and progression of neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. Its unique structure and its involvement in these diseases have made it an attractive target for drug development.

In addition to its involvement in cancer and neurodegenerative diseases, WFDC1 has also been shown to be involved in the development and progression of cardiovascular diseases. Studies have shown that high levels of WFDC1 are associated with the development of cardiovascular disease and that inhibition of WFDC1 has has been shown to be effective in treating cardiovascular disease.

Potential as a Biomarker

WFDC1 has also been shown to be a potential biomarker for various diseases. Its unique structure and its involvement in several disease processes have made it an attractive target for the development of biomarkers.

In cancer, WFDC1 has been shown to be involved in

Protein Name: WAP Four-disulfide Core Domain 1

Functions: Has growth inhibitory activity

The "WFDC1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about WFDC1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

WFDC10A | WFDC10B | WFDC11 | WFDC12 | WFDC13 | WFDC2 | WFDC21P | WFDC3 | WFDC5 | WFDC6 | WFDC8 | WFDC9 | WFIKKN1 | WFIKKN2 | WFS1 | WHAMM | WHAMMP1 | WHAMMP2 | WHAMMP3 | WHRN | WIF1 | WIPF1 | WIPF2 | WIPF3 | WIPI1 | WIPI2 | WIZ | WLS | WNK1 | WNK2 | WNK3 | WNK4 | Wnt | WNT1 | WNT10A | WNT10B | WNT11 | WNT16 | WNT2 | WNT2B | WNT3 | WNT3A | WNT4 | WNT5A | WNT5B | WNT6 | WNT7A | WNT7B | WNT8A | WNT8B | WNT9A | WNT9B | WRAP53 | WRAP73 | WRN | WRNIP1 | WSB1 | WSB2 | WSCD1 | WSCD2 | WSPAR | WT1 | WT1-AS | WTAP | WTAPP1 | WTIP | WWC1 | WWC2 | WWC2-AS2 | WWC3 | WWOX | WWP1 | WWP2 | WWTR1 | WWTR1-AS1 | XAB2 | XACT | XAF1 | XAGE-4 | XAGE1A | XAGE1B | XAGE1D | XAGE2 | XAGE3 | XAGE5 | XBP1 | XCL1 | XCL2 | XCR1 | XDH | XG | XGY2 | XIAP | XIRP1 | XIRP2 | XIST | XK | XKR3 | XKR4 | XKR5