Target Name: WFDC2
NCBI ID: G10406
Review Report on WFDC2 Target / Biomarker Content of Review Report on WFDC2 Target / Biomarker
WFDC2
Other Name(s): human epididymis protein 4 | putative protease inhibitor WAP5 | epididymis secretory sperm binding protein | Putative protease inhibitor WAP5 | WFDC2_HUMAN | Epididymal secretory protein E4 | WAP four-disulfide core domain 2 (isoform 2) | epididymis-specific, whey-acidic protein type, four-disulfide core | Epididymis-specific, whey-acidic protein type, four-disulfide core | epididymal secretory protein E4 | WFDC2 variant 2 | Major epididymis-specific protein E4 | WAP four-disulfide core domain 2 transcript variant 2 | dJ461P17.6 | WAP four-disulfide core domain protein 2 | WAP domain containing protein HE4-V4 | epididymal protein 4 | MGC57529 | WAP four-disulfide core domain 2 | major epididymis-specific protein E4 | EDDM4 | HE4 | WAP5

WFDC2: A Protein Regulator of Male Reproductive System and Health

The WFDC2 protein, also known as human epididymis protein 4, is a protein that is expressed in the epithelial cells of the human body. It is a 21-kDa protein that is involved in the regulation of various physiological processes that are important for maintaining the health and function of the male reproductive system.

WFDC2 is a key regulator of the development and maintenance of the vas deferens, which are the specialized structures that collect and transport sperm from the testicles to the prostate gland. During fetal development, the vas deferens migrate from the testicular cords to the prostate gland, where they form the vas deferens. These specialized structures help to ensure that sperm are properly collected and transported to the prostate gland, where they can be used for fertilization.

WFDC2 is also involved in the regulation of the production and release of other proteins that are important for the development and maintenance of the male reproductive system. For example, it has been shown to play a role in the regulation of the production of testosterone, which is a key androgen that helps to maintain the male reproductive system.

In addition to its role in the regulation of reproductive processes, WFDC2 is also involved in the regulation of various other physiological processes that are important for maintaining the health and function of the body. For example, it is involved in the regulation of inflammation, which is important for fighting off infections and protecting the body against damage.

WFDC2 is also involved in the regulation of cell signaling, which is important for the proper functioning of many different cell types in the body. It is part of a signaling pathway that helps to regulate the production and release of various proteins, including those that are involved in the regulation of growth, differentiation, and inflammation.

As a potential drug target, WFDC2 is an attractive target for researchers because of its involvement in the regulation of various important physiological processes. There is ongoing research into the use of drugs that can modulate the activity of WFDC2 in order to treat a variety of conditions, including male infertility and certain types of cancer.

In addition to its potential as a drug target, WFDC2 is also an interesting biomarker for the diagnosis and prognosis of various diseases. For example, studies have shown that levels of WFDC2 have been decreased in a variety of diseases, including certain types of cancer and male infertility. These changes in WFDC2 levels may be an important indicator of the severity of these diseases and can be used as a biomarker for the diagnosis and prognosis of these conditions.

Overall, WFDC2 is a protein that is involved in the regulation of various important physiological processes that are important for maintaining the health and function of the body. Its potential as a drug target and as a biomarker for the diagnosis and prognosis of various diseases makes it an attractive target for further research.

Protein Name: WAP Four-disulfide Core Domain 2

Functions: Broad range protease inhibitor

The "WFDC2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about WFDC2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

WFDC21P | WFDC3 | WFDC5 | WFDC6 | WFDC8 | WFDC9 | WFIKKN1 | WFIKKN2 | WFS1 | WHAMM | WHAMMP1 | WHAMMP2 | WHAMMP3 | WHRN | WIF1 | WIPF1 | WIPF2 | WIPF3 | WIPI1 | WIPI2 | WIZ | WLS | WNK1 | WNK2 | WNK3 | WNK4 | Wnt | WNT1 | WNT10A | WNT10B | WNT11 | WNT16 | WNT2 | WNT2B | WNT3 | WNT3A | WNT4 | WNT5A | WNT5B | WNT6 | WNT7A | WNT7B | WNT8A | WNT8B | WNT9A | WNT9B | WRAP53 | WRAP73 | WRN | WRNIP1 | WSB1 | WSB2 | WSCD1 | WSCD2 | WSPAR | WT1 | WT1-AS | WTAP | WTAPP1 | WTIP | WWC1 | WWC2 | WWC2-AS2 | WWC3 | WWOX | WWP1 | WWP2 | WWTR1 | WWTR1-AS1 | XAB2 | XACT | XAF1 | XAGE-4 | XAGE1A | XAGE1B | XAGE1D | XAGE2 | XAGE3 | XAGE5 | XBP1 | XCL1 | XCL2 | XCR1 | XDH | XG | XGY2 | XIAP | XIRP1 | XIRP2 | XIST | XK | XKR3 | XKR4 | XKR5 | XKR6 | XKR7 | XKR8 | XKR9 | XKRX | XKRY