Target Name: WFDC8
NCBI ID: G90199
Review Report on WFDC8 Target / Biomarker Content of Review Report on WFDC8 Target / Biomarker
WFDC8
Other Name(s): epididymis secretory protein Li 292 | WAP four-disulfide core domain 8, transcript variant a | Putative protease inhibitor WAP8 | testicular secretory protein Li 68 | WAP motif protein 1 | WFDC8_HUMAN | putative protease inhibitor WAP8 | dJ461P17.1 | WAP four-disulfide core domain 8 | Protease inhibitor WAP8 | protease inhibitor WAP8 | WAP8 | C20orf170 | epididymis secretory sperm binding protein | HEL-S-292 | WAP four-disulfide core domain protein 8 | WFDC8 variant a

WFDC8: A Potential Drug Target and Biomarker

WFDC8, or secretory protein Li 292, is a protein that has been identified as a potential drug target and biomarker for various diseases, including cancer, diabetes, and neurodegenerative disorders. In this article, we will explore the research on WFDC8 and its potential as a drug target.

Potential Drug Target

WFDC8 is a transmembrane protein that is expressed in various tissues and cells throughout the body. It is characterized by its extracellular domain, which consists of a catalytic domain and a transmembrane region. The catalytic domain of WFDC8 contains a zinc ion-dependent enzyme that is involved in the metabolism of lipids and proteins.

Research has shown that WFDC8 can be targeted by small molecules, such as inhibitors, to induce secretion of pro-inflammatory cytokines. These cytokines can then promote the recruitment of immune cells to the site of injury or disease, leading to an inflammatory response. This suggests that WFDC8 may be a potential drug target for diseases that are characterized by chronic inflammation.

Biomarker

WFDC8 has also been identified as a potential biomarker for various diseases. For example, researchers have shown that elevated levels of WFDC8 are associated with the development of neurodegenerative disorders, including Alzheimer's disease and Parkinson's disease. Additionally, high levels of WFDC8 have been shown to be associated with the development of cancer, including breast and ovarian cancer.

Potential Applications

The potential applications of WFDC8 are vast, and research is still in its early stages. One potential application of WFDC8 is as a drug target for neurodegenerative disorders. By inhibiting the activity of WFDC8, researchers may be able to develop new treatments for conditions such as Alzheimer's disease, Parkinson's disease, and other forms of dementia.

Another potential application of WFDC8 is as a biomarker for cancer. By detecting the levels of WFDC8 in cancer cells, researchers may be able to develop new tests for the early detection of cancer. Additionally, since WFDC8 is associated with the development of cancer, researchers may be able to use it as a marker for the effectiveness of cancer treatments.

Conclusion

WFDC8 is a protein that has been identified as a potential drug target and biomarker for various diseases. Its unique structure and function make it an attractive target for small molecules. Further research is needed to fully understand the potential applications of WFDC8, and to determine its effectiveness as a drug or biomarker.

Protein Name: WAP Four-disulfide Core Domain 8

The "WFDC8 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about WFDC8 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

WFDC9 | WFIKKN1 | WFIKKN2 | WFS1 | WHAMM | WHAMMP1 | WHAMMP2 | WHAMMP3 | WHRN | WIF1 | WIPF1 | WIPF2 | WIPF3 | WIPI1 | WIPI2 | WIZ | WLS | WNK1 | WNK2 | WNK3 | WNK4 | Wnt | WNT1 | WNT10A | WNT10B | WNT11 | WNT16 | WNT2 | WNT2B | WNT3 | WNT3A | WNT4 | WNT5A | WNT5B | WNT6 | WNT7A | WNT7B | WNT8A | WNT8B | WNT9A | WNT9B | WRAP53 | WRAP73 | WRN | WRNIP1 | WSB1 | WSB2 | WSCD1 | WSCD2 | WSPAR | WT1 | WT1-AS | WTAP | WTAPP1 | WTIP | WWC1 | WWC2 | WWC2-AS2 | WWC3 | WWOX | WWP1 | WWP2 | WWTR1 | WWTR1-AS1 | XAB2 | XACT | XAF1 | XAGE-4 | XAGE1A | XAGE1B | XAGE1D | XAGE2 | XAGE3 | XAGE5 | XBP1 | XCL1 | XCL2 | XCR1 | XDH | XG | XGY2 | XIAP | XIRP1 | XIRP2 | XIST | XK | XKR3 | XKR4 | XKR5 | XKR6 | XKR7 | XKR8 | XKR9 | XKRX | XKRY | XKRYP7 | XLOC_007697 | XLOC_008559 | XLOC_009911 | XNDC1N