ENPP5: Potential Drug Targets Or Biomarkers for Various Diseases

Target Name: ENPP5

NCBI ID: G59084

ENPP5

ENPP5: Potential Drug Targets Or Biomarkers for Various Diseases

ENPP5 (N-Acetyl-L-Cysteine 鈥嬧?婬ydrolase 5) is a protein that is expressed in various tissues throughout the body, including the brain, heart, and kidneys. It is a key enzyme in the detoxification process, breaking down a harmful compound called N-acetyl-L-cysteine 鈥嬧??(NAC) to less harmful compounds.

Recent studies have suggested that ENPP5 may have potential as a drug target or biomarker for various diseases, including cancer, neurodegenerative disorders, and autoimmune diseases.

One potential mechanism by which ENPP5 may be involved in cancer is its role in the detoxification of environmental toxins, such as oxalates and polycyclic aromatic hydrocarbons (PCBs). Many studies have shown that ENPP5 can significantly reduce the levels of these harmful compounds in the body, which may have a preventive effect on cancer.

ENPP5 may also be involved in the development and progression of neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease. The main characteristics of these diseases are neuronal death and neuronal damage, and the activity and expression levels of ENPP5 are related to the extent and severity of these diseases. Positively related.

In addition, ENPP5 may also be a potential biomarker for autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. These diseases are characterized by abnormal sensitivity and overreactivity of the immune system, and ENPP5 activity and expression levels may correlate with disease activity and severity..

ENPP5 is also expressed in various tissues throughout the body, including the brain, heart, and kidneys, which suggests that it may be involved in the detoxification of harmful substances in these organs.

In addition, ENPP5 may also be a potential drug target for various diseases, including cancer, neurodegenerative disorders, and autoimmune diseases.

In conclusion, ENPP5 is a protein that is expressed in various tissues throughout the body that may have potential as a drug target or biomarker for various diseases. Further research is needed to determine its specific role in the detoxification process and its potential as a therapeutic target .

Protein Name: Ectonucleotide Pyrophosphatase/phosphodiesterase Family Member 5

Functions: Can hydrolyze NAD but cannot hydrolyze nucleotide di- and triphosphates. Lacks lysopholipase D activity. May play a role in neuronal cell communication

The "ENPP5 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ENPP5 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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