AKTIP: Key Regulator of Metabolism, Inflammation and Stress Response

Target Name: AKTIP

NCBI ID: G64400

AKTIP

AKTIP: Key Regulator of Metabolism, Inflammation and Stress Response

AKTIP (AKT-interacting protein) is a protein that is expressed in various tissues throughout the body, including the brain, heart, and kidneys. It is a key regulator of the homeostasis of cells, and is involved in a wide range of physiological processes, including metabolism, inflammation, and stress response.

AKTIP is a protein that can interact with various other proteins, including the protein known as AKT (ATP-binding protein). This interaction between AKTIP and AKT is of particular interest, as it is thought to play a role in the regulation of cellular processes that are important for both the health and the disease.

One of the key functions of AKTIP is its role in the regulation of metabolism. AKTIP is involved in the production and breakdown of various types of lipids, including fatty acids, which are important for maintaining cellular energy homeostasis and for providing the building blocks for cell membranes. In addition, AKTIP is also involved in the regulation of carbohydrate metabolism, including the breakdown of glucose and the uptake of dietary carbohydrates.

AKTIP is also involved in the regulation of inflammation. It has been shown to play a role in the regulation of immune cell function and in the production of pro-inflammatory cytokines. In addition, AKTIP is also thought to play a role in the regulation of inflammation that is caused by injury or disease.

In addition to its role in metabolism and inflammation, AKTIP is also involved in the regulation of stress response. It has been shown to play a role in the regulation of cellular stress responses, including the regulation of the production of reactive oxygen species (ROS) that can cause damage to cells.

The AKTIP-AKT interaction is a complex process that is not yet fully understood. However, it is clear that this interaction is important for the regulation of cellular processes that are essential for both health and disease.

In conclusion, AKTIP is a protein that is of particular interest as a drug target or biomarker. Its role in the regulation of metabolism, inflammation, stress response, and other physiological processes makes it a promising target for manipulation for the treatment of a wide range of diseases. Further research is needed to fully understand the AKTIP-AKT interaction and its potential as a drug or biomarker.

Protein Name: AKT Interacting Protein

Functions: Component of the FTS/Hook/FHIP complex (FHF complex) (PubMed:32073997). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). Regulates apoptosis by enhancing phosphorylation and activation of AKT1. Increases release of TNFSF6 via the AKT1/GSK3B/NFATC1 signaling cascade. FHF complex promotes the distribution of AP-4 complex to the perinuclear area of the cell (PubMed:32073997)

The "AKTIP Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about AKTIP comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
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•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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