TMEM191C: A Potential Drug Target and Biomarker for Chronic Pain Management

Target Name: TMEM191C

NCBI ID: G645426

TMEM191C

TMEM191C: A Potential Drug Target and Biomarker for Chronic Pain Management

Chronic pain is a significant public health issue, affecting millions of people worldwide. The persistent nature of pain can have a significant impact on an individual's quality of life, leading to reduced productivity, increased stress, and even financial losses. As such, the development of new treatments for chronic pain is of great importance. In recent years, significant progress has been made in the understanding of the molecular mechanisms underlying chronic pain and the identification of potential drug targets. In this article, we focus on TMEM191C (Transmembrane Protein 191C), a protein that has been identified as a potential drug target and biomarker for chronic pain management.

TMEM191C: Structure and Function

TMEM191C is a member of the transmembrane protein (TMEM) family, which includes a diverse group of proteins that span various cellular processes, including cell signaling, proton transport, and drug transport. TMEM191C is characterized by a unique transmembrane topology, where the protein forms a monomeric complex with the endoplasmic reticulum (ER) and cytoplasmic side membrane (CSM). This unique structural feature allows TMEM191C to interact with various intracellular signaling pathways, including the TGF-β pathway.

TMEM191C is involved in several cellular processes that are crucial for maintaining cellular homeostasis. One of its key functions is the regulation of pain perception and neuroinflammation. TMEM191C has been shown to play a critical role in the regulation of pain transmission, as it has been shown to modulate the release of pro-inflammatory cytokines, such as TNF-伪 and IL-1尾, which are involved in the development of pain.

TMEM191C is also involved in the regulation of neuroinflammation, which is a significant contributor to the development of chronic pain. TMEM191C has been shown to play a crucial role in the regulation of the production of pro-inflammatory cytokines, such as TNF-伪, by neural stem/progenitor cells (NSCs) and microglia, which are involved in the development of neuroinflammation.

In addition to its role in pain perception and neuroinflammation, TMEM191C has also been shown to play a critical role in the regulation of cellular signaling pathways, including the TGF-β pathway. This pathway is involved in the regulation of cell proliferation, differentiation, and survival, and is a key factor in the development of chronic pain. TMEM191C has been shown to play a crucial role in the regulation of TGF-β signaling, as it has been shown to interact with the TGF-β receptor and to modulate the activity of the TGF-β pathway.

Drug Targeting and Biomarker Potential

The identification of TMEM191C as a potential drug target for chronic pain management has significant implications for the development of new treatments for chronic pain. By targeting TMEM191C, researchers may be able to reduce the production of pro-inflammatory cytokines, such as TNF-伪 and IL-1尾, which are involved in the development of pain. Additionally, TMEM191C may also be able to modulate the activity of the TGF-β pathway, which is involved in the regulation of cell proliferation and differentiation, which is a key factor in the development of chronic pain.

In addition to its potential therapeutic applications, TMEM191C also has significant potential as a biomarker for the diagnosis and monitoring of chronic pain. The regulation of pain perception and neuroinflammation is a critical factor in the development of chronic pain, and as such, TMEM191C may be a useful biomarker for the diagnosis and monitoring of chronic

Protein Name: Transmembrane Protein 191C

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•   general information;
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•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
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•   related combination drugs;
•   pharmacochemistry experiments;
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The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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