SLC5A5: Potential Drug Target and Biomarker for Hypertension, Heart Failure and Hypokalemia

Target Name: SLC5A5

NCBI ID: G6528

SLC5A5

SLC5A5: Potential Drug Target and Biomarker for Hypertension, Heart Failure and Hypokalemia

SLC5A5 (Sodium Chloride Transporter 5A5) is a protein that is expressed in most tissues and is responsible for transporting sodium ions (Na+) and chloride ions (Cl-) across cell membranes. It is a key component of the Na+/I- symport system, which is essential for maintaining the electrical balance of cells. SLC5A5 has been identified as a potential drug target and a biomarker for several diseases, including hypertension, heart failure, and hypokalemia (low potassium levels).

SLC5A5 is a member of the SLC gene family, which includes several other proteins that are involved in the transport of different ions across cell membranes. The SLC5A5 gene was first identified in 2003 and has since been extensively studied to determine its function and potential as a drug target.

SLC5A5 is expressed in most tissues and is involved in the transport of Na+ and Cl- ions across cell membranes. It is a key component of the Na+/I- symport system, which is essential for maintaining the electrical balance of cells. The Na+/I- symport system is a complex protein that consists of several subunits, including SLC5A1, SLC5A2, SLC5A3, and SLC5A4. SLC5A5 is one of the subunits of this system and is responsible for transporting Na+ and Cl- ions across the membrane.

SLC5A5 has been shown to be involved in several physiological processes in the body, including cell signaling, ion homeostasis, and neurotransmission. It has been shown to play a role in regulating the activity of several signaling pathways, including the Na+/Ca2+ signaling pathway and the neurotransmission pathway. SLC5A5 has also been shown to be involved in the regulation of ion channels, including the K+ channel.

SLC5A5 has been identified as a potential drug target due to its involvement in several diseases, including hypertension, heart failure, and hypokalemia. Hypertension, also known as high blood pressure, is a common condition that can lead to complications such as heart disease, stroke, and kidney damage. SLC5A5 has been shown to be involved in the regulation of blood pressure and has been shown to be a potential drug target for hypertension.

Heart failure is a condition that can occur due to a variety of factors, including heart muscle damage or deficiency of the heart muscle. SLC5A5 has been shown to be involved in the regulation of heart failure and has been shown to be a potential drug target for this disease. SLC5A5 has been shown to play a role in the regulation of ion homeostasis in the heart and has been shown to be involved in the regulation of the activity of several signaling pathways that are involved in heart function.

Hypokalemia, also known as low potassium levels, is a condition that can occur due to a variety of factors, including decreased intake of potassium-rich foods or certain medications. SLC5A5 has been shown to be involved in the regulation of potassium homeostasis and has been shown to be a potential drug target for hypokalemia. SLC5A5 has been shown to play a role in the regulation of ion channels in the potassium channels and has been shown to be involved in the regulation of the activity of several signaling pathways that are involved in potassium homeostasis.

In conclusion, SLC5A5 is a protein that is expressed in most tissues and is responsible for transporting sodium ions and chloride ions across cell membranes. It is a key component of the Na+/I- symport system and is involved in several physiological processes in the body. SLC5A5 has been identified as a potential drug target and a biomarker for several diseases, including hypertension, heart failure, and hypokalemia. Further research is needed to fully understand the role of SLC5A5 in these diseases and to develop effective treatments.

Protein Name: Solute Carrier Family 5 Member 5

Functions: Sodium:iodide symporter that mediates the transport of iodide into the thyroid gland (PubMed:8806637, PubMed:9329364, PubMed:20797386, PubMed:12488351, PubMed:18372236, PubMed:18708479, PubMed:31310151, PubMed:32084174). Can also mediate the transport of chlorate, thiocynate, nitrate and selenocynate (PubMed:12488351)

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•   the target screening and validation;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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