Target Name: SLIT3
NCBI ID: G6586
Review Report on SLIT3 Target / Biomarker Content of Review Report on SLIT3 Target / Biomarker
SLIT3
Other Name(s): slit homolog 3 protein | Slit2 | Slit-3 | slit guidance ligand 3 | Slit homolog 3 protein isoform 2 precursor (isoform 2) | SLIT3_HUMAN | multiple EGF-like domains protein 5 | SLIT3 variant 1 | SLIL2 | SLIT1 | slit homolog 3 | Multiple epidermal growth factor-like domains 5 | Slit homolog 3 protein | Multiple EGF-like domains protein 5 | KIAA0814 | SLIT3 variant 2 | Multiple epidermal growth factor-like domains protein 5 | Slit guidance ligand 3, transcript variant 1 | Slit guidance ligand 3, transcript variant 2 | Slit homolog 3 protein isoform 1 precursor (isoform 1) | MEGF5 | multiple epidermal growth factor-like domains protein 5 | slit2

SLIT3: Regulating Cell-Cell Adhesion, Proliferation, Migration, Tissue Repair and More

SLIT3, also known as slit homolog 3, is a protein that is expressed in many tissues throughout the body. It is a member of the SLIT family of proteins, which are known for their role in the development and maintenance of tissues and organs. SLIT3 is a 21-kDa protein that is expressed in a variety of tissues, including epithelial, muscle, and neural cells.

One of the key functions of SLIT3 is its role in cell-cell adhesion. Adhesion is the process by which cells stick together to form tissues and organs. SLIT3 is involved in this process by helping to regulate the stickiness of cells to each other.

SLIT3 is also involved in the regulation of cell proliferation. It has been shown to play a role in the G1/S transition, which is the process by which cells prepare for cell division. SLIT3 has been shown to promote the G1/S transition by activating the protein p21.

In addition to its role in cell-cell adhesion and proliferation, SLIT3 is also involved in the regulation of cell migration. It has been shown to play a role in the migration of neurons, which are a type of cell that is involved in the development and function of the nervous system.

SLIT3 is also involved in the regulation of tissue repair. When tissues are damaged, SLIT3 is involved in the process of tissue repair by helping to promote the growth of new cells.

SLIT3 is also involved in the regulation of cell signaling pathways. It has been shown to play a role in a variety of signaling pathways, including the TGF-β pathway and the Wnt pathway.

In addition to its role in cell-cell adhesion, proliferation, migration, and tissue repair, SLIT3 is also involved in the regulation of an important protein called tight junction. Tight junction is a type of protein that helps to keep cells in touch and prevent them from moving away from each other. SLIT3 is involved in the regulation of tight junctions by activating the protein Focal Adhesion Protein (FAP).

SLIT3 is also involved in the regulation of the cytoskeleton. The cytoskeleton is the structure that makes up the cell's skeleton, or support system. SLIT3 is involved in the regulation of the cytoskeleton by interacting with the protein microtubule protein and the protein Smoothestatin.

SLIT3 is also involved in the regulation of the cell cycle. It is a member of the microtubule protein 2 (MT2) family, which is involved in the regulation of the cell cycle by controlling the movement of microtubules.

In addition to its role in the regulation of the cell cycle, SLIT3 is also involved in the regulation of the apoptosis (programmed cell death). Apoptosis is the process by which cells die naturally, which is an important part of the immune system and helps to remove damaged or dysfunctional cells. SLIT3 is involved in the regulation of apoptosis by activating the protein Bcl-2.

SLIT3 is also involved in the regulation of inflammation. It has been shown to play a role in the regulation of inflammation by activating the protein NF-kappa-B.

In addition to its role in the regulation of inflammation, SLIT3 is also involved in the regulation of pain perception. It has been shown to play a role in the regulation of pain perception by activating the protein TrkA.

SLIT3 is also involved in the regulation of the development and progression of cancer. It has been shown to play a role in the regulation of cancer cell migration by activating the protein CXC.

In addition to its role in the regulation of cancer cell migration, SLIT3 is also involved in the regulation of the

Protein Name: Slit Guidance Ligand 3

Functions: May act as molecular guidance cue in cellular migration, and function may be mediated by interaction with roundabout homolog receptors

The "SLIT3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SLIT3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

SLIT3-AS2 | SLITRK1 | SLITRK2 | SLITRK3 | SLITRK4 | SLITRK5 | SLITRK6 | SLK | SLMAP | SLMO2-ATP5E | SLN | SLPI | SLTM | SLU7 | SLURP1 | SLURP2 | SLX1A | SLX1A-SULT1A3 | SLX1B | SLX1B-SULT1A4 | SLX4 | SLX4IP | SLX9 | SMAD | SMAD1 | SMAD1-AS1 | SMAD1-AS2 | SMAD2 | SMAD3 | SMAD4 | SMAD5 | SMAD5-AS1 | SMAD6 | SMAD7 | SMAD9 | SMAGP | Small Conductance Calcium-Activated Potassium Channel (SK) | SMAP1 | SMAP2 | SMARCA1 | SMARCA2 | SMARCA4 | SMARCA5 | SMARCAD1 | SMARCAD1-DT | SMARCAL1 | SMARCAL1-AS1 | SMARCB1 | SMARCC1 | SMARCC2 | SMARCD1 | SMARCD2 | SMARCD3 | SMARCE1 | SMC1A | SMC1B | SMC2 | SMC2-DT | SMC3 | SMC4 | SMC5 | SMC5-DT | SMC5-SMC6 Complex | SMC6 | SMCHD1 | SMCO1 | SMCO2 | SMCO3 | SMCO4 | SMCP | SMCR2 | SMCR5 | SMCR8 | SMDT1 | SMG1 | SMG1P1 | SMG1P2 | SMG1P3 | SMG1P4 | SMG1P5 | SMG5 | SMG6 | SMG7 | SMG7-AS1 | SMG8 | SMG9 | SMILR | SMIM1 | SMIM10 | SMIM10L1 | SMIM10L2A | SMIM10L2B | SMIM11 | SMIM12 | SMIM13 | SMIM14 | SMIM15 | SMIM17 | SMIM18 | SMIM19