SLC9A8: Potential Drug Target for Cancer and Other Cellular Processes

Target Name: SLC9A8

NCBI ID: G23315

SLC9A8

SLC9A8: Potential Drug Target for Cancer and Other Cellular Processes

SLC9A8 (FLJ42500) is a protein that is expressed in various tissues throughout the body. It is a member of the long non-coding RNA (lncRNA) family and is located on chromosome 9. SLC9A8 has been shown to play a role in various cellular processes, including cell signaling, DNA replication, and metabolism.

One of the most significant aspects of SLC9A8 is its role in cancer. SLC9A8 has been shown to promote the growth and survival of various cancer cell types, including breast, ovarian, and colorectal cancer. This is achieved through various mechanisms, such as increasing the expression of genes involved in cell growth and survival, and by inhibiting the activity of genes that promote cell death.

In addition to its role in cancer, SLC9A8 has also been shown to be involved in a number of other cellular processes. For example, it has been shown to play a role in cell signaling and metabolism, and has been shown to interact with a number of different proteins. SLC9A8 has also been shown to play a role in the regulation of DNA replication, and has been shown to interact with the protein responsible for copying DNA in the cell.

Despite its potential as a drug target, SLC9A8 has not yet been studied extensively. There are currently no drugs that are specifically designed to target SLC9A8, and more research is needed to fully understand its role in various cellular processes. However, because of its role in cancer and its potential as a drug target, SLC9A8 is an intriguing molecule that is worth further research.

Protein Name: Solute Carrier Family 9 Member A8

Functions: Na(+)/H(+) antiporter. Mediates the electoneutral exchange of intracellular H(+) ions for extracellular Na(+) in 1:1 stoichiometry (PubMed:15522866). Acts as an Na(+)/H(+) exchanger in the trans-Golgi. Contributes to the regulation of pH regulation of Golgi apparatus, and consequently, in protein trafficking and endosomal morphology (PubMed:15522866, PubMed:20719963). In germ cells, plays a crucial role in acrosome biogenesis and sperm development, probably by playing a role in the fusion of the Golgi-derived vesicles that form the acrosomal cap (By similarity). Can also be active at the cell surface of specialized cells. In the small intestine, at the cell membrane, plays a major physiological role in transepithelial absorption of Na(+) and regulates intracellular pH homeostasis of intestinal epithelial cells (PubMed:34288721). Acts as an important regulator of mucosal integrity in the intestine and in the stomach, could mediate the pH fluctuation necessary for mucin exocytosis or assist membrane trafficking of other proteins (By similarity). Plays a role in photoreceptor survival and in the maintenance of intracellular pH homeostasis in retinal pigment epithelium (RPE cells) (By similarity)

The "SLC9A8 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SLC9A8 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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